Document Detail

Bacterial behaviors associated with the quorum-sensing peptide pheromone ('alarmone') in streptococci.
MedLine Citation:
PMID:  23642115     Owner:  NLM     Status:  In-Data-Review    
Streptococci are among the predominant bacterial species living in the human body. They are normally harmless bacteria, but have the ability to cause diverse infections, ranging from mild (e.g., tooth decay and sore throat) to life-threatening (e.g., endocarditis and meningitis). Streptococci have evolved various means of coping with the deleterious effects of environmental stressors and avoiding the host immune system. Recently, several studies have shown that streptococci colonizing the mouth and upper respiratory tract are able to mount complex stress responses in order to persist and successfully survive competition in their ecological niche. Using a small quorum-sensing peptide pheromone acting as a stress-inducible 'alarmone', oral streptococci synchronize the gene expression of a specific group of cells to coordinate important biological activities.
Delphine Dufour; Céline M Lévesque
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Future microbiology     Volume:  8     ISSN:  1746-0921     ISO Abbreviation:  Future Microbiol     Publication Date:  2013 May 
Date Detail:
Created Date:  2013-05-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101278120     Medline TA:  Future Microbiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  593-605     Citation Subset:  IM    
Dental Research Institute, Faculty of Dentistry, University of Toronto, 124 Edward St, Room 454B, Toronto, ON, M5G 1G6, Canada.
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