| Bacterial Hydrolysis of Host Glycoproteins - Powerful Protein Modification and Efficient Nutrient Acquisition. | |
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MedLine Citation:
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PMID: 22222876 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Glycoproteins are ubiquitous in nature and fundamental to most biological processes, including the human immune system. The glycoprotein carbohydrate moieties, or glycans, are very diverse in their structure and composition, and have major effects on the chemical, physical and biological properties of these glycoproteins. The hydrolysis of glycoprotein glycans by bacterial glycosidases can have dramatic effects on glycoprotein function and, thereby, be beneficial for the bacteria in different ways. This review gives an introduction to the expanding field of extracellular glycosidases from bacterial pathogens with activity on host glycoproteins, describes some known and proposed consequences for the host and the bacteria and discusses some evolutionary and regulatory aspects of bacterial glycosidases. |
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Authors:
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Julia Garbe; Mattias Collin |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-03 |
Journal Detail:
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Title: Journal of innate immunity Volume: - ISSN: 1662-8128 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-6 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101469471 Medline TA: J Innate Immun Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 S. Karger AG, Basel. |
Affiliation:
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Department of Clinical Sciences, Division of Infection Medicine, Lund University Biomedical Center B14, Lund, Sweden. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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