| Bacteria in supragingival plaque samples can be killed by low-power laser light in the presence of a photosensitizer. | |
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MedLine Citation:
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PMID: 7759386 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The purpose of this study was to determine whether bacteria in supragingival plaque samples could be killed by low-power laser light in the presence of a suitable photosensitizer. Plaque samples were obtained from 10 volunteers, treated with either toluidine blue O (TBO) or aluminum disulphonated phthalocyanine (AlPcS2), and then exposed to light from a helium/neon (HeNe) or gallium aluminium arsenide (GaAs) laser respectively. Following irradiation, substantial reductions were achieved in the total anaerobic count as well as in the number of viable streptococci and actinomyces present in the samples. In the absence of laser light, the sensitizers themselves had little effect on the viability of the bacteria in the plaque samples. The HeNe/TBO combination appeared to be more effective than the GaAs/AlPcS2 combination, achieving log10 reductions of 2.95, 5.40 and 3.34 in the total anaerobic count, streptococci and actinomyces respectively with a light energy dose of 1.31 J. If effective in vivo, lethal photosensitization may be useful as a means of eliminating plaque bacteria from a carious lesion prior to its restoration. |
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Authors:
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M Wilson; T Burns; J Pratten; G J Pearson |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of applied bacteriology Volume: 78 ISSN: 0021-8847 ISO Abbreviation: J. Appl. Bacteriol. Publication Date: 1995 May |
Date Detail:
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Created Date: 1995-06-27 Completed Date: 1995-06-27 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7503050 Medline TA: J Appl Bacteriol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 569-74 Citation Subset: IM |
Affiliation:
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Department of Microbiology, Eastman Dental Institute for Oral Health Care Sciences, University of London, UK. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Actinomyces
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drug effects,
radiation effects* Dental Plaque / microbiology* Gingiva / microbiology Humans Indoles / pharmacology Lasers* Organometallic Compounds / pharmacology Photosensitizing Agents / pharmacology Streptococcus / drug effects, radiation effects* Tolonium Chloride / pharmacology |
| Chemical | |
Reg. No./Substance:
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0/Indoles; 0/Organometallic Compounds; 0/Photosensitizing Agents; 68637-19-4/aluminum phthalocyanine disulfonate; 92-31-9/Tolonium Chloride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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