| Bacteria and asthma: more there than we thought. | |
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MedLine Citation:
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PMID: 21702654 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Evaluation of: Huang YJ, Nelson CE, Brodie EL et al. Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma. J. Allergy Clin. Immunol. 127(2), 372-381, e371-e373 (2011). In a recently performed case-control study, characteristics of the airway microbiota in suboptimally controlled adult asthmatics were compared with those of healthy, nonasthmatic adult subjects. Bacterial burden was significantly greater in asthmatic subjects. Further, increased airway microbiota variability and diversity were correlated with increased bronchial hyper-responsiveness. Although several limitations are present, this study provides an intriguing initial insight into the possible relationship between the airway microbiota and asthma pathogenesis. |
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Authors:
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Daniel E Dulek; R Stokes Peebles |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Expert review of respiratory medicine Volume: 5 ISSN: 1747-6356 ISO Abbreviation: Expert Rev Respir Med Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-06-27 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101278196 Medline TA: Expert Rev Respir Med Country: England |
Other Details:
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Languages: eng Pagination: 329-32 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Division of Pediatric Infectious Diseases, Monroe Carell Jr, Children's Hospital at Vanderbilt, Vanderbilt University Medical Center, Nashville, TN, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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