Document Detail


Bacteremia and MR-proANP changes in mild community-acquired pneumonia.
MedLine Citation:
PMID:  22103585     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Background: Mid-regional pro-atrial natriuretic peptide (MR-proANP) increases with severity in community-acquired pneumonia (CAP). We investigated whether changes of MR-proANP correlated to bacteremia. Methods: 392 adult patients with CAP visiting emergency department from a prospective observational multicenter study. Results: MR-proANP levels increased in patients with positive bacteremia (92.8 pmol/L vs. 84.3 pmol/L, p = 0.04). Performance of MR-proANP to detect bacteremia (0.60) was equivalent to CRP (0.59) but less accurate than PCT (0.69). Conclusion: MR-ANP poorly predicts bacteremia in CAP patients.
Authors:
Solweig Guinard-Barbier; Camille Chenevier-Gobeaux; Sophie Grabar; Laurent Quinquis; Jeannot Schmidt; Pierre Hausfater; Enrique Casalino; Stéphanie Huet; Jean-Louis Pourriat; Bertrand Renaud; Yann-Erick Claessens
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals     Volume:  16     ISSN:  1366-5804     ISO Abbreviation:  Biomarkers     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-11-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9606000     Medline TA:  Biomarkers     Country:  England    
Other Details:
Languages:  eng     Pagination:  637-41     Citation Subset:  IM    
Affiliation:
Department of Emergency Medicine, Groupe Hospitalier Broca Cochin Hôtel-Dieu , Paris , France.
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