| Background, but not foreground, spatial cues are taken as references for head direction responses by rat anterodorsal thalamus neurons. | |
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MedLine Citation:
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PMID: 11425881 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two populations of limbic neurons are likely neurophysiological substrates for cognitive operations required for spatial orientation and navigation: hippocampal pyramidal cells discharge selectively when the animal is in a certain place (the "firing field") in the environment, whereas head direction cells discharge when the animal orients its head in a specific, "preferred" direction. Cressant et al. (1997) showed that the firing fields of hippocampal place cells reorient relative to a group of three-dimensional objects only if these are at the periphery, but not the center of an enclosed platform. To test for corresponding responses in head direction cells, three objects were equally spaced along the periphery of a circular platform. Preferred directions were measured before and after the group of objects was rotated. (The rat was disoriented in total darkness between sessions). This was repeated in the presence or absence of a cylinder enclosing the platform. When the enclosure was present, the preferred directions of all 30 cells recorded shifted by the same angle as the objects. In the absence of the enclosure, the preferred directions did not follow the objects, remaining fixed relative to the room. These results provide a possible neurophysiological basis for observations from psychophysical experiments in humans that background, rather than foreground, cues are preferentially used for spatial orientation. |
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Authors:
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M B Zugaro; A Berthoz; S I Wiener |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Journal of neuroscience : the official journal of the Society for Neuroscience Volume: 21 ISSN: 1529-2401 ISO Abbreviation: J. Neurosci. Publication Date: 2001 Jul |
Date Detail:
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Created Date: 2001-07-04 Completed Date: 2001-07-26 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8102140 Medline TA: J Neurosci Country: United States |
Other Details:
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Languages: eng Pagination: RC154 Citation Subset: IM |
Affiliation:
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Centre National de la Recherche Scientifique, Collège de France, Laboratoire de Physiologie de la Perception et de l'Action, 75231 Paris CEDEX 05, France. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Anterior Thalamic Nuclei / physiology* Cues* Depth Perception / physiology Electrodes, Implanted Environment Head / physiology Male Neurons / physiology* Orientation / physiology* Rats Rats, Long-Evans Rotation Space Perception / physiology* Spatial Behavior / physiology Wakefulness |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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