Document Detail


Babesiosis. Diagnostic pitfalls.
MedLine Citation:
PMID:  1645925     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A case of babesiosis complicated by quinine-induced hemolysis is described. A splenectomized woman contracted babesiosis after visiting an endemic area. The patient presented with high fevers and minimal hemolysis. While she was on treatment, the hemolysis increased. The increased hemolysis was initially attributed to babesiosis, but after additional evaluation quinine therapy was found to be the cause. In the setting of this brisk hemolysis, there was an increase in red blood cell inclusions. At first, the inclusions were thought to be Babesia, but iron stain demonstrated that many of the inclusions were hemolysis-induced Pappenheimer bodies. The role of the clinical laboratory in sorting out this confusing picture is presented.
Authors:
J M Carr; S Emery; B F Stone; L Tulin
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of clinical pathology     Volume:  95     ISSN:  0002-9173     ISO Abbreviation:  Am. J. Clin. Pathol.     Publication Date:  1991 Jun 
Date Detail:
Created Date:  1991-07-05     Completed Date:  1991-07-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370470     Medline TA:  Am J Clin Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  774-7     Citation Subset:  AIM; IM    
Affiliation:
Department of Pathology, Beth Israel Hospital, Boston, Massachusetts 02215.
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MeSH Terms
Descriptor/Qualifier:
Adult
Animals
Babesia / isolation & purification
Babesiosis / diagnosis*
Diagnostic Errors
Erythrocytes / parasitology,  ultrastructure
Female
Hemolysis
Humans
Inclusion Bodies / ultrastructure
Quinine / adverse effects
Splenectomy
Chemical
Reg. No./Substance:
130-95-0/Quinine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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