| BOLD-MRI cerebrovascular reactivity findings in cocaine-induced cerebral vasculitis. | |
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MedLine Citation:
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PMID: 18839005 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: An 18-year-old woman presented to a regional stroke center with dysphasia and right hemiparesis 2 days after consuming alcohol and inhaling cannabis and -- for the first time -- cocaine. INVESTIGATIONS: Physical examination, blood tests for inflammatory markers, vasculitis and toxicology screen, echocardiography, electrocardiography, CT scanning, brain MRI, magnetic resonance angiography, magnetic resonance vessel wall imaging, catheter angiography, and correlation of blood oxygen level-dependent (BOLD)-MRI signal intensity with changes in end-tidal partial pressure of carbon dioxide. DIAGNOSIS: Cocaine-induced cerebral vasculitis. MANAGEMENT: No specific therapy was initiated. The patient's vital signs and neurological status were monitored during her admission. Follow-up medical imaging was performed after the patient's discharge from hospital. |
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Authors:
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Jay S Han; Daniel M Mandell; Julien Poublanc; Alexandra Mardimae; Marat Slessarev; Cheryl Jaigobin; Joseph A Fisher; David J Mikulis |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2008-10-07 |
Journal Detail:
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Title: Nature clinical practice. Neurology Volume: 4 ISSN: 1745-8358 ISO Abbreviation: - Publication Date: 2008 Nov |
Date Detail:
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Created Date: 2008-11-03 Completed Date: 2009-03-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101261799 Medline TA: Nat Clin Pract Neurol Country: England |
Other Details:
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Languages: eng Pagination: 628-32 Citation Subset: IM |
Affiliation:
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Department of Physiology at the University of Toronto, Toronto, ON, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Alcohol Drinking / adverse effects Brain / blood supply, pathology, physiopathology Brain Mapping Central Nervous System Depressants / adverse effects Cerebrovascular Circulation / drug effects* Cocaine / adverse effects* Female Humans Infarction, Middle Cerebral Artery / chemically induced, pathology, physiopathology Magnetic Resonance Angiography Magnetic Resonance Imaging Marijuana Smoking / adverse effects Vasculitis, Central Nervous System / chemically induced*, pathology, physiopathology Vasoconstrictor Agents / adverse effects* |
| Chemical | |
Reg. No./Substance:
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0/Central Nervous System Depressants; 0/Vasoconstrictor Agents; 50-36-2/Cocaine |
| Comments/Corrections | |
Comment In:
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Nat Clin Pract Neurol. 2008 Nov;4(11):579
[PMID:
18978798
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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