Document Detail


BNP levels in patients with long-term exposure to biomass fuel and its relation to right ventricular function.
MedLine Citation:
PMID:  20466065     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
METHODS: Our study population consisted of 39 female patients with BFE (group 1) and, 31 control subjects (group 2). Pulmonary function tests and transthoracic echocardiographic examination were performed. Right ventricular volumes, diameters and tissue velocities were obtained by tissue Doppler echocardiography. BNP levels were measured and correlated to right ventricular measurements and pulmonary artery pressure.
RESULTS: In BFE group, obstructive and restrictive spirometric findings were found. RV diameters, volumes and pulmonary artery pressure were higher in group 1 than group 2. BNP levels were well correlated with right ventricular end diastolic diameter and pulmonary artery pressure. A suspicion is also arised that toxic chemicals in biomass fuel may play a role in RV dysfunction.
CONCLUSION: Biomass fuel exposure not only cause obstructive and/or restrictive lung disease but also leads to systolic and diastolic right ventricular dysfunction. BNP levels may be used to monitor pulmonary artery pressure and right ventricular enlargement in these patients.
Authors:
Yunus Emiroglu; Ramazan Kargin; Feyza Kargin; Mustafa Akcakoyun; Selcuk Pala; Halil Mutlu; Murat Akcay; Soe Moe Aung; Reha Baran; Nihal Ozdemir
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Publication Detail:
Type:  Journal Article     Date:  2010-05-11
Journal Detail:
Title:  Pulmonary pharmacology & therapeutics     Volume:  23     ISSN:  1522-9629     ISO Abbreviation:  Pulm Pharmacol Ther     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-08-11     Completed Date:  2010-12-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9715279     Medline TA:  Pulm Pharmacol Ther     Country:  England    
Other Details:
Languages:  eng     Pagination:  420-4     Citation Subset:  IM    
Copyright Information:
Crown Copyright 2010. Published by Elsevier Ltd. All rights reserved.
Affiliation:
Department of Cardiology, Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital, Istanbul, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Aged
Air Pollution, Indoor / adverse effects*
Biological Markers / blood
Biomass
Cooking
Cross-Sectional Studies
Echocardiography, Doppler
Female
Heating
Humans
Manure
Middle Aged
Natriuretic Peptide, Brain / blood*
Pulmonary Artery / physiopathology,  ultrasonography
Respiratory Function Tests
Smoke / adverse effects*
Ventricular Dysfunction, Right / blood,  etiology,  physiopathology*
Wood
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Manure; 0/Smoke; 114471-18-0/Natriuretic Peptide, Brain

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