Document Detail


A B(1) -insensitive high resolution 2D T(1) mapping pulse sequence for dGEMRIC of the HIP at 3 Tesla.
MedLine Citation:
PMID:  21688318     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Early detection of cartilage degeneration in the hip may help prevent onset and progression of osteoarthritis in young patients with femoroacetabular impingement. Delayed gadolinium-enhanced MRI of cartilage is sensitive to cartilage glycosaminoglycan loss and could serve as a diagnostic tool for early cartilage degeneration. We propose a new high resolution 2D T(1) mapping saturation-recovery pulse sequence with fast spin echo readout for delayed gadolinium-enhanced magnetic resonance imaging of cartilage of the hip at 3 T. The proposed sequence was validated in a phantom and in 10 hips, using radial imaging planes, against a rigorous multipoint saturation-recovery pulse sequence with fast spin echo readout. T(1) measurements by the two pulse sequences were strongly correlated (R(2) > 0.95) and in excellent agreement (mean difference = -8.7 ms; upper and lower 95% limits of agreement = 64.5 and -81.9 ms, respectively). T(1) measurements were insensitive to B(1+) variation as large as 20%, making the proposed T(1) mapping technique suitable for 3 T. Magn Reson Med, 2011. © 2011 Wiley-Liss, Inc.
Authors:
Riccardo Lattanzi; Christian Glaser; Artem V Mikheev; Catherine Petchprapa; David J Mossa; Soterios Gyftopoulos; Henry Rusinek; Michael Recht; Daniel Kim
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-6-17
Journal Detail:
Title:  Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine     Volume:  -     ISSN:  1522-2594     ISO Abbreviation:  -     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-6-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8505245     Medline TA:  Magn Reson Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Wiley-Liss, Inc.
Affiliation:
Department of Radiology, Center for Biomedical Imaging, New York University Langone Medical Center, New York, New York, USA; Department of Radiology, New York University Langone Medical Center, New York, New York, USA. riccardo.lattanzi@nyumc.org.
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