Document Detail


B-type natriuretic peptide utilization as an adjunct to management in a case of conjoined twins with pulmonary hypertension.
MedLine Citation:
PMID:  20085871     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This article reports a case of pulmonary hypertension in 37-week-gestational-age, pygopagus conjoined twins where B-type natriuretic peptide (BNP) was used as a cost-effective and important tool to aid effective management. Pulmonary hypertension in neonates is associated with high morbidity and mortality and multiplies the challenge of caring for conjoined twins. BNP is a peptide hormone secreted by cardiac ventricles that have undergone stress related to ventricular filling, volume overload, and pressure. BNP is commonly used in adults to assess heart failure, but its utility is less established in infants receiving neonatal intensive care. In this case, BNP testing was used as an adjunct to standard assessments for rapid diagnosis which was critical to expediting appropriate treatment management for these high-risk patients.
Authors:
Vladana Milisavljevic; Isabell B Purdy; Cindy Le
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Neonatal network : NN     Volume:  29     ISSN:  1539-2880     ISO Abbreviation:  Neonatal Netw     Publication Date:    2010 Jan-Feb
Date Detail:
Created Date:  2010-01-20     Completed Date:  2010-04-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8503921     Medline TA:  Neonatal Netw     Country:  United States    
Other Details:
Languages:  eng     Pagination:  5-12     Citation Subset:  N    
Affiliation:
David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
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MeSH Terms
Descriptor/Qualifier:
Biological Markers / metabolism
Diseases in Twins / metabolism*,  therapy*
Dose-Response Relationship, Drug
Female
Humans
Hypertension, Pulmonary / metabolism*,  therapy*
Infant
Natriuretic Peptide, Brain / metabolism*
Treatment Outcome
Twins, Conjoined*
Vasoconstrictor Agents / therapeutic use
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Vasoconstrictor Agents; 114471-18-0/Natriuretic Peptide, Brain

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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