Document Detail

B-type natriuretic peptide levels in patients with paroxysmal lone atrial fibrillation.
MedLine Citation:
PMID:  16715186     Owner:  NLM     Status:  MEDLINE    
To investigate the levels of B-type natriuretic peptide (BNP) in patients with atrial fibrillation (AF) but without structural heart disease, we measured plasma BNP concentration in 61 consecutive AF patients and in 61 age- and sex-matched healthy subjects. Plasma BNP concentration in the AF group was significantly higher than in the control group (121+/-32 vs 41+/-12 pg/ml, P<0.001). Logistic regression analysis showed that age (r=0.66, P<0.001), left atrial diameter (r=0.59, P<0.01), and a history of AF (r=0.72, P<0.001) were independent predictors of elevated BNP. We concluded that BNP was elevated in patients with paroxysmal lone AF. The clinical significance of BNP elevation in these patients requires further investigation.
Jingtian Li; Lexin Wang
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Heart and vessels     Volume:  21     ISSN:  0910-8327     ISO Abbreviation:  Heart Vessels     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-05-22     Completed Date:  2007-05-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8511258     Medline TA:  Heart Vessels     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  137-40     Citation Subset:  IM    
Department of Cardiology, The Affiliated Hospital of Weifang Medical College, Shandong Province, P.R. China.
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MeSH Terms
Atrial Fibrillation / blood*,  drug therapy,  pathology,  physiopathology
Heart Atria / pathology
Middle Aged
Natriuretic Peptide, Brain / blood*
Ventricular Function, Left
Reg. No./Substance:
114471-18-0/Natriuretic Peptide, Brain

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