Document Detail


B-cell lineage acute lymphoblastic leukemia with i(7q) and t(9;9)(p22;p24).
MedLine Citation:
PMID:  2963687     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 61-year-old Japanese male with acute lymphoblastic leukemia (ALL) is reported. Surface marker examinations revealed that the leukemic cells were of a B-cell lineage; the cells had common ALL antigens, Ia-like antigens, and B1 and B4 antigens. Chromosome analysis showed abnormalities of t(9;9)(p22;p24), as well as an isochromosome for the long arm of chromosome 7. The heritable fragile site at 9p was not detected in the peripheral blood cells of this patient at remission phase.
Authors:
T Takeda; A Takagi; Y Zaike; M Hirai; M Kawakami; M Mori; K Ohyashiki; T Ikeuchi
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cancer genetics and cytogenetics     Volume:  30     ISSN:  0165-4608     ISO Abbreviation:  Cancer Genet. Cytogenet.     Publication Date:  1988 Feb 
Date Detail:
Created Date:  1988-03-30     Completed Date:  1988-03-30     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7909240     Medline TA:  Cancer Genet Cytogenet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  295-9     Citation Subset:  IM    
Affiliation:
Department of Laboratory Medicine and Hematology Section, Tokyo Metropolitan Geriatric Hospital, Japan.
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MeSH Terms
Descriptor/Qualifier:
Antigens, Neoplasm / analysis
B-Lymphocytes / immunology
Chromosomes, Human, Pair 7*
Chromosomes, Human, Pair 9*
Humans
Karyotyping
Leukemia, Lymphoid / genetics*
Male
Middle Aged
Neprilysin
Translocation, Genetic*
Tumor Markers, Biological / analysis
Chemical
Reg. No./Substance:
0/Antigens, Neoplasm; 0/Tumor Markers, Biological; EC 3.4.24.11/Neprilysin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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