Document Detail

Azithromycin, Ureaplasma and chronic lung disease of prematurity: a case study for neonatal drug development.
MedLine Citation:
PMID:  21697219     Owner:  NLM     Status:  Publisher    
Chronic lung disease of prematurity (CLD) remains a major cause of morbidity and mortality in preterm infants. Ureaplasma has received intermittent attention over the last two decades as a possible contributory factor. In addition, pulmonary inflammation is associated with the development of CLD. The macrolide azithromycin provides an attractive option to determine if it can decrease the development of CLD as it has both anti-inflammatory and anti-infective properties. In this article, the authors review the evidence for the role of Ureaplasma in the development of CLD and the obstacles faced in the development of a drug before it reaches clinical practice.
Mark A Turner; Evelyne Jacqz-Aigrain; Sailesh Kotecha
Related Documents :
12149499 - Human adenovirus and human cytomegalovirus infections in preterm newborns: no associati...
7745509 - Double-blind evaluation of developmental and health status to age 2 years of infants we...
2191259 - Drug therapy for bronchopulmonary dysplasia.
8604659 - Use of the intramuscular relative-dose-response test to predict bronchopulmonary dyspla...
15574629 - Prophylaxis of early adrenal insufficiency to prevent bronchopulmonary dysplasia: a mul...
24363249 - Influence of smoking and alcohol during pregnancy on outcome of vlbw infants.
15271069 - White monkey syndrome in infant baboons (papio species).
16174639 - Amylin peptide levels are raised in infants of diabetic mothers.
2637919 - Correlation between adolescent nutrition during pregnancy and outcome of low birth-weig...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-6-22
Journal Detail:
Title:  Archives of disease in childhood     Volume:  -     ISSN:  1468-2044     ISO Abbreviation:  -     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-6-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372434     Medline TA:  Arch Dis Child     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Women's and Children's Health, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Development of ovarian hyperstimulation syndrome: interrogation of key proteins and biological proce...
Next Document:  No longer lost in translation: the art and science of sports injury prevention implementation resear...