| Azetidine-2-carboxylic acid in garden beets (Beta vulgaris). | |
| | |
MedLine Citation:
|
PMID: 16516254 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Azetidine-2-carboxylic acid (L-Aze) is a toxic and teratogenic non-protein amino acid. In many species, including man, L-Aze is misincorporated into protein in place of proline, altering collagen, keratin, hemoglobin, and protein folding. In animal models of teratogenesis, it causes a wide range of malformations. The role of L-Aze in human disease has been unexplored, probably because the compound has not been associated with foods consumed by humans. Herein we report the presence of L-Aze in the garden or table beet (Beta vulgaris). |
| | |
Authors:
|
Edward Rubenstein; Haihong Zhou; Karolina M Krasinska; Allis Chien; Christopher H Becker |
Related Documents
:
|
19055734 - The role of polyamines in protein-dependent hypoxic tolerance of drosophila. 1367454 - A molecular biological approach to reducing dietary amino acid needs. 10335374 - Lysinoalanine in food and in antimicrobial proteins. 189854 - The thermal polymerization of amino acids in the presence of sand. 2574974 - Zonation of fatty acid metabolism in rat liver. 20886594 - Acid-catalyzed dehydration of fructose and inulin with glycerol or glycerol carbonate a... |
Publication Detail:
|
Type: Journal Article Date: 2006-03-03 |
Journal Detail:
|
Title: Phytochemistry Volume: 67 ISSN: 0031-9422 ISO Abbreviation: Phytochemistry Publication Date: 2006 May |
Date Detail:
|
Created Date: 2006-04-25 Completed Date: 2006-08-16 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0151434 Medline TA: Phytochemistry Country: United States |
Other Details:
|
Languages: eng Pagination: 898-903 Citation Subset: IM |
Affiliation:
|
School of Medicine, Stanford University, CA 94305, USA. gim@med.stanford.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Azetidinecarboxylic Acid
/
analogs & derivatives,
chemistry* Beta vulgaris / chemistry* Chromatography, Liquid Mass Spectrometry Molecular Structure Plant Tubers / chemistry Proline / analogs & derivatives Teratogens / chemistry |
| Chemical | |
Reg. No./Substance:
|
0/Teratogens; 147-85-3/Proline; 2517-04-6/Azetidinecarboxylic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Spontaneous motor activity in fat-fed, streptozotocin-treated rats: a nonobese model of type 2 diabe...
Next Document: Bispectral index, spectral edge frequency 95% and median frequency recorded at varying desflurane co...