| Ayurvedic medicine zinc bhasma: physicochemical evaluation, anti-diabetic activity and safety assessment. | |
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MedLine Citation:
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PMID: 21485845 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Bhasmas are unique Ayurvedic metallic preparations used for medicinal purposes since ancient times. With increasing knowledge of risk of nanomaterials, it becomes imperative to assess the safety of nanoparticulate Ayurvedic medicines using toxicity models. In this study, zinc bhasma was characterized using modern physicochemical techniques. In vitro toxicity test revealed no major cytotoxicity at all the dose levels tested. No behavioral abnormality, clinical signs and mortality was seen indicating no adverse effects. SGOT, SGPT and serum urea were also not significantly altered indicating no major organ toxicity. In the current study, zinc bhasma appears safe for human use. |
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Authors:
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Rinku D Umrani; Kishore M Paknikar |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of biomedical nanotechnology Volume: 7 ISSN: 1550-7033 ISO Abbreviation: J Biomed Nanotechnol Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-04-13 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101230869 Medline TA: J Biomed Nanotechnol Country: United States |
Other Details:
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Languages: eng Pagination: 148-9 Citation Subset: IM |
Affiliation:
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Centre for Nanobioscience, Agharkar Research Institute, G. G. Agarkar Road, Pune 411004, India. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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