| Axonal transport of gangliosides in the goldfish optic nerve. | |
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MedLine Citation:
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PMID: 5049309 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Radioactive glucosamine and N-acetylmannosamine injected into the goldfish eye are incorporated into gangliosides that undergo rapid axonal transport to the optic nerve terminals. All ganglioside fractions are labeled. These data provide the first evidence that axonal transport has a role in neuronal ganglioside function and metabolism. |
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Authors:
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D S Forman; R W Ledeen |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Science (New York, N.Y.) Volume: 177 ISSN: 0036-8075 ISO Abbreviation: Science Publication Date: 1972 Aug |
Date Detail:
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Created Date: 1972-09-29 Completed Date: 1972-09-29 Revised Date: 2011-12-27 |
Medline Journal Info:
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Nlm Unique ID: 0404511 Medline TA: Science Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 630-3 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Axons / metabolism* Biological Transport Carbon Isotopes Chromatography, Thin Layer Cyprinidae Gangliosides / biosynthesis, isolation & purification, metabolism* Glucosamine / metabolism Hexosamines / metabolism Mannose / metabolism Optic Nerve / analysis, metabolism* Retina / metabolism Tritium |
| Chemical | |
Reg. No./Substance:
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0/Carbon Isotopes; 0/Gangliosides; 0/Hexosamines; 10028-17-8/Tritium; 31103-86-3/Mannose; 3416-24-8/Glucosamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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