Document Detail


Axon trajectories in local circuits of the primary motor cortex in the macaque monkey (Macaca fuscata).
MedLine Citation:
PMID:  11223469     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The intrinsic trajectories and terminal arbors of two axons and one horizontal axon collateral within the primary motor cortex (M1) were studied in the macaque monkey using injections of biotinylated dextran amine (BDA) into the putative primary forelimb motor cortex, and two-dimensional (2-D) reconstruction of the individually labeled axons and collateral. (1) A long collateral of the main axon from a large pyramidal cell in layer Vb of the putative forelimb area on the anterior bank of the central sulcus coursed horizontally anteriorly for 3 mm and formed a terminal arbor in layer III of M1. (2) The main axon of a pyramidal cell in layer IIIa+b of the putative forelimb area on the precentral gyrus descended into the white matter and then entered the anterior bank of the central sulcus to form a terminal arbor in layers III and V. (3) The main axon of a pyramidal cell in layer IIIc of the putative forelimb area on the precentral gyrus descended and bifurcated in the white matter. One branch entered the anterior bank of the central sulcus to form a terminal field in layer VI. These results indicate that some local axons and horizontal axon collaterals arising from M1 reach their single targets within M1 to form single terminal fields.
Authors:
A Yamashita; T Arikuni
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Neuroscience research     Volume:  39     ISSN:  0168-0102     ISO Abbreviation:  Neurosci. Res.     Publication Date:  2001 Feb 
Date Detail:
Created Date:  2001-03-06     Completed Date:  2001-05-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8500749     Medline TA:  Neurosci Res     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  233-45     Citation Subset:  IM    
Affiliation:
Department of Anatomy, Nihon University School of Medicine, 30-1 Oyaguchi-Kamimachi, Itabashi-ku, 173-0032, Tokyo, Japan.
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MeSH Terms
Descriptor/Qualifier:
Animals
Axonal Transport
Axons / physiology*,  ultrastructure
Biotin / analogs & derivatives*
Dextrans
Fluorescent Dyes
Forelimb / innervation
Macaca / anatomy & histology,  physiology*
Motor Cortex / anatomy & histology,  cytology,  physiology*
Neural Pathways / anatomy & histology,  physiology
Pyramidal Cells / cytology,  physiology*
Chemical
Reg. No./Substance:
0/Fluorescent Dyes; 0/biotinylated dextran amine; 58-85-5/Biotin; 9004-54-0/Dextrans

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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