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Axillary artery pseudoaneurysm after plate osteosynthesis for a clavicle nonunion: A case report and literature review.
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PMID:  21472068     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Neurovascular complications have been reported from both plate osteosynthesis and intramedullary fixation of midshaft clavicle fractures. We wish to report a case of limb threatening ischemia from screw penetration of the axillary artery after plate osteosynthesis for a clavicle nonunion. A literature review of vascular trauma from midshaft clavicle fractures is presented.
Authors:
Gregory I Bain; Ian J Galley; Angus R E Keogh; Adam W Durrant
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of shoulder surgery     Volume:  4     ISSN:  0973-6042     ISO Abbreviation:  Int J Shoulder Surg     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2011-04-07     Completed Date:  2011-07-14     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101291740     Medline TA:  Int J Shoulder Surg     Country:  South Africa    
Other Details:
Languages:  eng     Pagination:  79-82     Citation Subset:  -    
Affiliation:
Modbury Public Hospital, Modbury, South Australia.
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Journal Information
Journal ID (nlm-ta): Int J Shoulder Surg
Journal ID (publisher-id): IJSS
ISSN: 0973-6042
Publisher: Medknow Publications, India
Article Information
© International Journal of Shoulder Surgery
open-access:
Print publication date: Season: Jul–Sep Year: 2010
Volume: 4 Issue: 3
First Page: 79 Last Page: 82
ID: 3063347
PubMed Id: 21472068
Publisher Id: IJSS-4-79
DOI: 10.4103/0973-6042.76969

Axillary artery pseudoaneurysm after plate osteosynthesis for a clavicle nonunion: A case report and literature review
Gregory I. BainAF0001
Ian J. Galley1
Angus R. E. KeoghAF0001
Adam W. DurrantAF0001
Modbury Public Hospital, Modbury, South Australia
1Royal Adelaide Hospital, Adelaide, South Australia
Correspondence: Address for correspondence: Mr Gregory Bain 196 Melbourne St, North Adelaide, 5006, Australia, E-mail: greg@gregbain.com.au

INTRODUCTION

Clavicle fractures are common, accounting for 5–12% of all fractures.[1, 2] The results of non-operative management of middle third clavicle fractures are typically good with a rate of nonunion between 0.1 and 5%.[1, 3, 4] Internal fixation of clavicle fractures in patients with a high risk of nonunion has been advocated.[59] Appreciation of the negative effect on shoulder function of clavicle shortening,[1012] the availability of anatomy specific locking plates and intramedullary devices has also increased the popularity of clavicle fixation.

Neurovascular complications have been reported from both plate osteosynthesis[1315] and intramedullary fixation of midshaft clavicle fractures.[16]

We wish to report a case of limb threatening ischemia from screw penetration of the axillary artery after plate osteosynthesis for a clavicle nonunion. A literature review of vascular trauma from midshaft clavicle fractures is presented.


CASE REPORT

A 32-year-old male carpet layer suffered a closed fracture to his nondominant left clavicle in 1998. He was treated non-operatively and went on to develop a symptomatic nonunion. Open reduction and bone grafting of the nonunion was performed in 1999 with a six-hole AO small fragment dynamic compression plate (DCP) (Synthes®).

The clavicle united and his symptoms resolved. He presented 6 years after his surgery, with 18 months of progressively worsening pain, paraesthesia and claudication in his left hand. In the week prior to presentation, he noticed that his left hand was cool and pale.

Clinically, he had a well-healed scar over his left clavicle with no associated mass or bruit. His left axillary artery was palpable. However, his brachial, radial and ulnar arteries were not. He had pain in the hand with exertion and poor capillary return. There were no trophic changes. His upper limb neurology was normal.

Plain radiographs demonstrated a united clavicle with a six-hole plate superiorly. The medial screw was prominent inferiorly [Figure 1].

An arteriogram demonstrated the medial screw penetrating the axillary artery with an associated pseudoaneurysm [Figure 2]. There was occlusion of the brachial artery above the elbow [Figure 3] with slow filling of the ulnar artery via collateral vessels. The radial artery and the proximal one-third of the ulnar artery were occluded. There was little flow past the metacarpophalangeal (MCP) joints. A computed tomography (CT) arteriogram confirmed penetration of the axillary artery by the prominent medial screw, with an associated pseudoaneurysm [Figures 4 and 5].

The patient was anticoagulated following plate removal [Figure 6]. The prominent medial screw measured 26 mm.

The pseudoaneurysm was bypassed using an 8 mm by 25 mm Viabahn® (W. L. Gore and Associates, Flagstaff, AZ, USA) stent placed in the axillary artery via a femoral approach. The self-expanding stent is constructed with a durable, reinforced biocompatible, expanded polytetrafluoroethylene (ePTFE) liner attached to the external nitinol stent structure.

The stent was dilated using a 7 mm×40 mm balloon [Figure 7].


DISCUSSION

Iatrogenic vascular injury from internal fixation of midshaft clavicle fractures is rare, with only three other reported cases from plate osteosynthesis. Johnson[14] reported a case of left arm ischemia presenting 22 months after internal fixation of an acute fracture. A pseudoaneurysm with occlusion of the brachial artery was found. Ligation of the subclavian artery followed by carotid-axillary bypass grafting resulted in a symptom-free left arm.

Casselman[13] reported a similar case, 8 years following internal fixation of a nonunion. The pseudoaneurysm and first rib was resected via a transclavicular approach. Interposition grafting was performed using Gor-Tex (W. L. Gore and Associates, Flagstaff, AZ, USA). The clavicle was bone grafted and internally fixed at the end of the procedure.

Shackford[15] reported a case, 10 years following internal fixation of a midshaft nonunion. Angiography confirmed a pseudoaneurysm with screw penetration of the subclavian artery and occlusion of the brachial artery. Resection of the pseudoaneurysm confirmed screw penetration of the artery. Interposition vein grafting and claviculectomy gave a good clinical result.

All cases had a delayed presentation ranging from 22 months to 10 years following internal fixation. It is possible that the prominent screw erodes through the arterial wall with shoulder movement. Another explanation is that the artery is injured at the time of injury or surgery and forms a pseudoaneurysm, which was found in all cases. The upper limb has an extensive collateral circulation[17] particularly around the shoulder and elbow. This allowed all four patients to present with claudication symptoms rather than critical ischemia despite occlusion of the brachial artery.

There have been multiple reported cases of vascular injuries from midshaft clavicle fractures.[1824] These include arterial and venous lacerations and arterial pseudoaneurysms.[2532] Death from vascular injury secondary to clavicle fracture has been reported.[33, 34] The most famous case is that of Sir Robert Peel (1788–1850) who created the police force in Great Britain. Subclavian vein thrombosis (Paget–Schroetter’s syndrome)[3537] from clavicle fracture and pulmonary emboli from this thrombus[38] has been reported.

Nonoperative treatments for psuedoaneurysms, such as external ultrasound compression and transcatheter coiling, have been used at other sites. However, they are not suitable for the subclavian artery. Ultrasound guided thrombin injections have been successfully used for a subclavian pseudoaneurysm.[39] There is, however, a risk of occluding one of the branches supplying cerebral circulation.

Surgical treatment can be performed by means of a supraclavicular incision and can be combined with clavicular resection. Access to the proximal subclavian artery may require a median sternotomy or a thoracotomy through the third or fourth intercostal space on the left.[18, 20]

Endovascular stenting, as was used in this case, has been used previously for pseudoaneurysm associated with a clavicle fracture.[29, 40] It has the advantage of being minimally invasive with a remote access site. Potential problems include late stenosis and fracture of the stents. Newer flexible drug eluting stents may prevent this problem.[29]

This case reminds us of the importance of careful screw placement for osteosynthesis of the clavicle. The proximity of the clavicle and subclavian artery has previously been described[41] and it is suggested that screws for osteosynthesis of the clavicle be no longer than 18 mm in order to avoid the subclavian artery. Pseudoaneurysm of the subclavian artery in this instance was successfully treated with a closed procedure. However, there is the potential for significant morbidity.


Notes

Source of Support: Nil

Conflict of Interest: None declared.

The authors would like to acknowledge Ron Heptinstall RN and the Modbury Hospital Foundation for help in preparation of this manuscript.


REFERENCES
1. Basamania C,Craig E,Rockwood CJ. Rockwood C,Matsen III F,Wirth MFractures of the clavicleThe ShoulderYear: 2004PhiladelphiaWB Saunders Co455
2. Rowe CR. An atlas of anatomy and treatment of midclavicular fracturesClin Orthop Relat ResYear: 19685829425666865
3. Neer CS 2nd. Nonunion of the clavicleJ Am Med AssocYear: 196017210061114426324
4. Robinson CM. Fractures of the clavicle in the adult: Epidemiology and classificationJ Bone Joint Surg BrYear: 199880476849619941
5. Brinker MR,Edwards TB,O’Connor DP. Estimating the risk of nonunion following nonoperative treatment of a clavicular fractureJ Bone Joint Surg AmYear: 200587676715741641
6. Gossard JM. Closed treatment of displaced middle-third fractures of the clavicle gives poor resultsJ Bone Joint Surg BrYear: 1998805589619962
7. Hill JM,McGuire MH,Crosby LA. Closed treatment of displaced middle third fractures of the clavicle gives poor resultsJ Bone Joint Surg BrYear: 19977953799250733
8. Robinson CM,Court-Brown CM,McQueen MM,Wakefield AE. Estimating the risk of nonunion following nonoperative treatment of a clavicular fractureJ Bone Joint Surg AmYear: 200486-A13596515252081
9. Wick M,Muller EJ,Kollig E,Muhr G. Midshaft fractures of the clavicle with a shortening of more than 2 cm predispose to nonunionArch Orthop Trauma SurgYear: 20011212071111317682
10. Chan KY,Jupiter JB,Leffert RD,Marti R. Clavicle malunionJ Shoulder Elbow SurgYear: 199982879010471996
11. Ledger M,Leeks N,Ackland T,Wang A. Short malunions of the clavicle: An anatomic and functional studyJ Shoulder Elbow SurgYear: 2005143495416015232
12. McKee MD,Wild LM,Schemitsch EH. Midshaft malunions of the clavicleJ Bone Joint Surg AmYear: 200385-A790712728026
13. Casselman F,Vanslembroek K,Verougstraete L. An unusual cause of thoracic outlet syndromeJ TraumaYear: 19974314239253927
14. Johnson B,Thursby P. Subclavian artery injury caused by a screw in a clavicular compression plateCardiovasc SurgYear: 1996441458782951
15. Shackford SR,Connolly JF. Taming of the screw: A case report and literature review of limb-threatening complications after plate osteosynthesis of a clavicular nonunionJ TraumaYear: 200355840314608153
16. Ring D,Holovacs T. Brachial plexus palsy after intramedullary fixation of a clavicular fracture.A report of three casesJ Bone Joint Surg AmYear: 2005871834716085627
17. Levin PM,Rich NM,Hutton JE Jr. Collaternal circulation in arterial injuriesArch SurgYear: 197110239295553313
18. Costa MC,Robbs JV. Nonpenetrating subclavian artery traumaJ Vasc SurgYear: 198887153385881
19. Howard FM,Shafer SJ. Injuries to the clavicle with neurovascular complications. A study of fourteen casesJ Bone Joint Surg AmYear: 1965471335464284420
20. Katras T,Baltazar U,Rush DS,Davis D,Bell TD,Browder IW,et al. Subclavian arterial injury associated with blunt traumaVasc SurgYear: 200135435011668368
21. Klier I,Mayor P. Laceration of the innominate internal jugular venous junction: Rare complications of fracture of the clavicleOrthop RevYear: 198110812
22. Natali J,Maraval M,Kieffer E,Petrovic P. Fractures of the clavicle and injuries of the sub-clavian artery. Report of 10 casesJ Cardiovasc Surg (Torino)Year: 1975165417
23. Penn I. The vascular complications of fractures of the clavicleJ TraumaYear: 196448193114225329
24. Tse DH,Slabaugh PB,Carlson PA. Injury to the axillary artery by a closed fracture of the clavicle. A case reportJ Bone Joint Surg AmYear: 198062137247440617
25. Cayford EH,Tees FJ. Traumatic aneurysm of the subclavian artery as a late complication of fractured clavicleCan Med Assoc JYear: 193125450220318476
26. Debakey ME,Beall AC Jr,Wukasch DC. Recent developments in vascular surgery with particular reference to orthopaedicsAm J SurgYear: 19651091344214261637
27. Gryska PF. Major vascular injuries. Principal of management in selected cases of arterial and venous injuryN Engl J MedYear: 1962266381513902492
28. Hansky B,Murray E,Minami K,Korfer R. Delayed brachial plexus paralysis due to subclavian pseudoaneurysm after clavicular fractureEur J Cardiothorac SurgYear: 1993749788217229
29. Renger RJ,de Bruijn AJ,Aarts HC,van der Hem LG. Endovascular treatment of a pseudoaneurysm of the subclavian arteryJ TraumaYear: 2003559697114608176
30. Serrano JA,Rodriguez P,Castro L,Serrano P,Carpintero P. Acute subclavian artery pseudoaneurysm after closed fracture of the clavicleActa Orthop BelgYear: 200369555714748115
31. Shih JS,Chao EK,Chang CH. Subclavian pseudoaneurysm after clavicle fractureTaiwan Yi Xue Hui Za ZhiYear: 19838233256576108
32. Yates DW. Complications of fractures of the clavicleInjuryYear: 19767189931254331
33. Dickson J. Death following fractured clavicleBMJYear: 19522666 Death following fractured clavicle BMJ 1952;2:666.
34. Kendall KM,Burton JH,Cushing B. Fatal subclavian artery transection from isolated clavicle fractureJ TraumaYear: 200048316810697095
35. Hughes ES. Venous obstruction in the upper extremity; Paget-Schroetter’s syndrome; a review of 320 casesSurg Gynecol ObstetYear: 1949888912718108679
36. Lim EV,Day LJ. Subclavian vein thrombosis following fracture of the clavicle. A case reportOrthopedicsYear: 198710349513562354
37. Steinberg I. Subclavian vein thrombosis associated with fractures of the clavicleN Engl J MedYear: 19612646868
38. Scarpa FJ,Levy RM. Pulmonary embolism complicating clavicle fractureConn MedYear: 1979437713540499
39. McConnell PI,Rehm J,Oltman DL,Lynch TG,Baxter BT. Thrombin injection for treating a subclavian artery pseudoaneurysmSurgeryYear: 2000127716810840372
40. Pfammatter T,Kunzli A,Hilfiker PR,Schubiger C,Turina M. Relief of subclavian venous and brachial plexus compression syndrome caused by traumatic subclavian artery aneurysm by means of transluminal stent-graftingJ TraumaYear: 19984597249820711
41. Galley IJ,Watts AC,Bain GI. The anatomic relationship of the axillary artery and vein to the clavicle: A cadaveric studyJ Shoulder Elbow SurgYear: 200918e21519362855

Figures

[Figure ID: F0001]
Figure 1 

Plain radiograph of left clavicle. (AC: Acromion. CL: Clavicle. R: 1st rib). Arrow depicts prominent medial screw lateral to the 1st rib



[Figure ID: F0002]
Figure 2 

Arteriogram. AA: axillary artery. (SA: Subclavian artery). Arrow depicts penetration of the axillary artery by the prominent medial screw. A pseudoaneurysm has formed. The axillary artery is filled with contrast distal to the pseudoaneurysm



[Figure ID: F0003]
Figure 3 

Arteriogram at level of left elbow. The arrow indicates occlusion of the brachial artery. Sluggish distal perfusion is provided via collateral vessels at the level of the elbow



[Figure ID: F0004]
Figure 4 

CT arteriogram of left clavicle, demonstrating penetration of the axillary artery by the prominent medial screw with associated pseudoaneurysm of the axillary artery. All structures apart from the clavicle and subclavian and axillary arteries have been subtracted



[Figure ID: F0005]
Figure 5 

Coronal 2D reconstruction CT arteriogram of left shoulder. (AA: axillary artery; C: Coracoid process; R: 1st rib; SA: Subclavian artery). Arrow depicts prominent screw with associated pseudoaneurysm. The subclavian artery becomes the axillary artery at the lateral border of the first rib. The subclavian artery lies in a groove on the superior aspect of the 1st rib



[Figure ID: F0006]
Figure 6 

Arteriogram of left subclavian and axillary artery following removal of internal fixation. (AA: Axillary artery; PA: Pseudoaneurysm; SA: Subclavian artery)



[Figure ID: F0007]
Figure 7 

Arteriogram of left subclavian and axillary artery following insertion of 8 mm×25 mm Viabahn® (WL Gore, Flagstaff, AZ, USA) endoprosthesis, shown by arrow, after balloon dilation with 7 mm×40 mm balloon. (AA: Axillary artery; SA: Subclavian artery). The neck of the pseudoaneurysm has been occluded



Article Categories:
  • Case Report

Keywords: Clavicle, fracture, nonunion, pseudoaneurysm.

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