Document Detail


Axial area and anteroposterior diameter as estimates of left atrial size using computed tomography of the chest: comparison with 3-dimensional volume.
MedLine Citation:
PMID:  20159629     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Left atrial (LA) size has incremental value in risk stratification.
OBJECTIVES: We aimed to assess feasibility and reproducibility of 2 quick measures of LA size by chest CT (axial LA area and LA anteroposterior [AP] diameter) by using contrast-enhanced and CT scans.
METHODS: We measured LA size in 100 contrast-enhanced 64-slice multidetector CT (MDCT) scans (randomly selected from the ROMICAT collective) by (1) axial LA area at the level of the left ventricular outflow tract and the mitral valve leaflets, (2) AP diameter in 3-chamber view, and (3) 3-dimensional (3D) LA volume by Simpson's methods. We assessed interobserver and intraobserver intraclass correlation coefficient (ICC) for axial LA area and AP diameter as well as their correlation to 3D LA volume. For axial area, feasibility and reproducibility were also determined in 100 non-contrast MDCT scans, randomly selected from the Framingham Heart Offspring collective.
RESULTS: In contrast-enhanced CT, both LA axial area and AP diameter had excellent reproducibility (interobserver: axial area: ICC, 0.96, mean relative difference, 2.4% +/- 7.4%; AP diameter: ICC, 0.91, 3.6% +/- 7.2%; intraobserver: axial area: ICC, 0.99, 0.4% +/- 5.2%; AP diameter: ICC, 0.94, 1.7% +/- 5.5%). Correlations with 3D volume were better for axial area (r=0.88) than for AP diameter (r=0.67). In non-contrast images, axial area could be assessed with excellent reproducibility (interobserver: ICC, 0.96, 0.5% +/- 8.3%; intraobserver: ICC, 0.99, 0.01% +/- 4.4%).
CONCLUSION: Both AP diameter and axial LA area permit quick and reproducible estimates of LA volume in contrast-enhanced and non-contrast electrocardiographic-gated chest CT. However, LA area should be used preferably over AP diameter because of its better agreement to 3D LA volume.
Authors:
Amir A Mahabadi; Quynh A Truong; Christopher L Schlett; Bharat Samy; Christopher J O'Donnell; Caroline S Fox; Fabian Bamberg; Udo Hoffmann
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2009-11-27
Journal Detail:
Title:  Journal of cardiovascular computed tomography     Volume:  4     ISSN:  1876-861X     ISO Abbreviation:  J Cardiovasc Comput Tomogr     Publication Date:    2010 Jan-Feb
Date Detail:
Created Date:  2010-02-17     Completed Date:  2010-05-19     Revised Date:  2014-09-08    
Medline Journal Info:
Nlm Unique ID:  101308347     Medline TA:  J Cardiovasc Comput Tomogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  49-54     Citation Subset:  IM    
Copyright Information:
2010 Society of Cardiovascular Computed Tomography. All rights reserved.
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MeSH Terms
Descriptor/Qualifier:
Algorithms*
Aortography / methods*
Female
Humans
Imaging, Three-Dimensional / methods*
Male
Middle Aged
Organ Size
Radiographic Image Enhancement / methods
Radiographic Image Interpretation, Computer-Assisted / methods*
Radiography, Thoracic / methods*
Reproducibility of Results
Sensitivity and Specificity
Tomography, X-Ray Computed / methods*
Triiodobenzoic Acids / diagnostic use*
Grant Support
ID/Acronym/Agency:
K23 HL098370/HL/NHLBI NIH HHS; L30 HL093806/HL/NHLBI NIH HHS; L30 HL093806-01/HL/NHLBI NIH HHS; L30HL093896/HL/NHLBI NIH HHS; N01 HC025195/HC/NHLBI NIH HHS; N01-HC-25195/HC/NHLBI NIH HHS; R01 HL080053/HL/NHLBI NIH HHS; R01 HL080053/HL/NHLBI NIH HHS; R01 HL080053-03/HL/NHLBI NIH HHS; T32HL076136/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Triiodobenzoic Acids; 92339-11-2/iodixanol
Comments/Corrections
Comment In:
J Cardiovasc Comput Tomogr. 2010 Jan-Feb;4(1):55-7   [PMID:  20159630 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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