| Axial (Spinal) Gout. | |
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MedLine Citation:
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PMID: 22318623 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Gout is a common metabolic disorder resulting from supersaturation of uric acid in extracellular fluid and deposition of monosodium urate crystals in tissues. Gouty arthritis typically affects the peripheral joints of the appendicular skeleton, especially the feet and hands. Gouty involvement of the spine, however, is not as rare as generally perceived. Although it may be asymptomatic, tophaceous axial gout is also a well-documented cause of acute back pain, radiculopathy, and frank cord compression. As with the appendicular skeleton, it takes several years of gout before radiological evidence of erosive change or tophi is apparent in the axial skeleton. This is best detected by CT imaging. The sequelae of cord compression can be reversed with timely surgical intervention and maintenance of uric acid-lowering therapy. The long-term effects of urate-lowering therapies on axial gout have not been studied. |
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Authors:
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Elena Lumezanu; Rukmini Konatalapalli; Arthur Weinstein |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-2-9 |
Journal Detail:
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Title: Current rheumatology reports Volume: - ISSN: 1534-6307 ISO Abbreviation: - Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-2-9 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100888970 Medline TA: Curr Rheumatol Rep Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Washington Hospital Center, Rheumatology 2A-66, 110 Irving Street, NW, Washington, DC, 20010, USA, elena.m.lumezanu@medstar.net. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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