| Avoiding bias from aggregate measures of exposure. | |
| | |
MedLine Citation:
|
PMID: 17435216 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Sometimes in descriptive epidemiology or in the evaluation of a health intervention policy change, proportions exposed to a risk factor or to an intervention are used as explanatory variables in log-linear regressions for disease incidence or mortality. AIM: To demonstrate how estimates from such models can be substantially inaccurate as estimates of the effect of the risk factor or intervention at individual level. To show how the individual level effect can be correctly estimated by excess relative risk models. METHODS: The problem and solution are demonstrated using data on prostate-specific antigen testing and prostate cancer incidence. |
| | |
Authors:
|
Stephen W Duffy; Håkan Jonsson; Olorunsola F Agbaje; Nora Pashayan; Rhian Gabe |
Related Documents
:
|
12173176 - Uncertainty in exposure estimates made by modeling versus monitoring. 16126766 - A database of exposures in the rubber manufacturing industry: design and quality control. 1579756 - Statistical validation of intermediate endpoints for chronic diseases. 6532426 - Statistical design, analysis, and inference issues in studies using sister chromatid ex... 22209756 - A comprehensive three-dimensional dynamic model of the human head and trunk for estimat... 21431766 - Integrating high-throughput pyrosequencing and quantitative real-time pcr to analyze co... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of epidemiology and community health Volume: 61 ISSN: 0143-005X ISO Abbreviation: J Epidemiol Community Health Publication Date: 2007 May |
Date Detail:
|
Created Date: 2007-04-16 Completed Date: 2007-07-10 Revised Date: 2013-06-06 |
Medline Journal Info:
|
Nlm Unique ID: 7909766 Medline TA: J Epidemiol Community Health Country: England |
Other Details:
|
Languages: eng Pagination: 461-3 Citation Subset: IM |
Affiliation:
|
Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Charterhouse Square, London EC1M 6BQ, UK. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Bias (Epidemiology)* Humans Logistic Models Risk Risk Assessment |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Effect of conjugal bereavement on mortality of the bereaved spouse in participants of the Renfrew/Pa...
Next Document: Association of the tensin N-terminal protein-tyrosine phosphatase domain with the alpha isoform of p...