Document Detail


Avoidance of vitamin D deficiency in pregnancy in the United Kingdom: the case for a unified approach in National policy.
MedLine Citation:
PMID:  20594390     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Prevalence of hypovitaminosis D in Western populations is high; pregnant women are identified as a high-risk group, especially if dark skinned. Consequences of severe clinical vitamin D deficiency in pregnancy can be life threatening to the newborn, while lesser degrees of hypovitaminosis D may have important long-term implications for offspring health. Past experiences with routine provision of 10 microg/d (400 IU/d) to all pregnant mothers suggest that this dose is sufficient to prevent overt neonatal complications of vitamin D deficiency. Recent data suggest that supplementation with dosages above 10 microg/d may be required for optimal health in the mother and child; however, further research is required for the assessment of the benefits and safety of supplementation with higher dosages. Lack of unified advice on vitamin D supplementation of pregnant mothers in the UK hinders the implementation of primary prevention strategies and is likely to leave some deficient mothers without supplementation.
Authors:
Elina Hyppönen; Barbara J Boucher
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-07-02
Journal Detail:
Title:  The British journal of nutrition     Volume:  104     ISSN:  1475-2662     ISO Abbreviation:  Br. J. Nutr.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-21     Completed Date:  2010-08-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372547     Medline TA:  Br J Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  309-14     Citation Subset:  IM    
Affiliation:
MRC Centre of Epidemiology for Child Health, UCL Institute of Child Health and Centre for Paediatric Epidemiology and Biostatistics, 30 Guilford Street, London, UK. e.hypponen@ich.ucl.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Dietary Supplements*
Female
Great Britain / epidemiology
Humans
Infant, Newborn
Maternal Nutritional Physiological Phenomena
Nutrition Policy*
Pregnancy
Pregnancy Complications / prevention & control*
Prenatal Exposure Delayed Effects / prevention & control*
Vitamin D / administration & dosage*,  therapeutic use
Vitamin D Deficiency / epidemiology,  prevention & control*
Grant Support
ID/Acronym/Agency:
//Department of Health; //Medical Research Council
Chemical
Reg. No./Substance:
1406-16-2/Vitamin D
Comments/Corrections
Comment In:
Br J Nutr. 2010 Aug;104(3):315-7   [PMID:  20646333 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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