Document Detail

Avascular necrosis of the metacarpals in juvenile dermatomyositis.
MedLine Citation:
PMID:  20577093     Owner:  NLM     Status:  MEDLINE    
Avascular necrosis (AVN) of the metacarpal heads is uncommon and has been associated with trauma, systemic lupus erythematosus, and corticosteroid usage. There have been no previous reports of metacarpal AVN described in patients with juvenile dermatomyositis. Descriptions of AVN in juvenile dermatomyositis are rare. We present 2 cases of patients with juvenile dermatomyositis who developed multifocal avascular necrosis after corticosteroid therapy with unusual distribution and review the literature on metacarpal AVN.
Angela Byun Robinson; C Egla Rabinovich
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases     Volume:  16     ISSN:  1536-7355     ISO Abbreviation:  J Clin Rheumatol     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-27     Completed Date:  2010-12-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9518034     Medline TA:  J Clin Rheumatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  233-6     Citation Subset:  IM    
Division of Pediatric Rheumatology, Duke University Medical Center, Durham, NC 27710, USA.
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MeSH Terms
Adrenal Cortex Hormones / adverse effects*,  therapeutic use
Dermatomyositis / complications*,  drug therapy
Metacarpal Bones / pathology*
Osteonecrosis / chemically induced*,  diagnosis*,  pathology
Treatment Outcome
Reg. No./Substance:
0/Adrenal Cortex Hormones

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