| Availability of cardio-ankle vascular index (CAVI) as a screening tool for atherosclerosis. | |
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MedLine Citation:
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PMID: 18219171 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: A novel index, the cardio-ankle vascular index (CAVI), which reflects the stiffness of the aorta, femoral artery, and tibial artery, was recently developed by measuring brachial - ankle pulse wave velocity and blood pressure. METHODS AND RESULTS: In the present study 1,014 Japanese adults from the general population were screened to clarify the correlation between CAVI and other existing markers related to atherosclerosis, including carotid intima - media thickness (CIMT) and homocysteine (HCY). CAVI was strongly associated with age in both men and women. After adjustment for age and sex, CAVI was correlated with systolic and diastolic blood pressures. In addition, CAVI was significantly correlated with total cholesterol hemoglobin A(1c) and total HCY, as well as CIMT. CONCLUSION: CAVI is an appropriate screening tool for atherosclerosis, but further studies are needed to establish a convenient and effective screening system using it. |
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Authors:
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Koichiro Kadota; Noboru Takamura; Kiyoshi Aoyagi; Hironori Yamasaki; Toshiro Usa; Mio Nakazato; Takahiro Maeda; Mitsuhiro Wada; Ken-ichiro Nakashima; Koh Abe; Fuminao Takeshima; Yoshiyuki Ozono |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Circulation journal : official journal of the Japanese Circulation Society Volume: 72 ISSN: 1346-9843 ISO Abbreviation: Circ. J. Publication Date: 2008 Feb |
Date Detail:
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Created Date: 2008-01-25 Completed Date: 2008-05-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101137683 Medline TA: Circ J Country: Japan |
Other Details:
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Languages: eng Pagination: 304-8 Citation Subset: IM |
Affiliation:
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Department of General Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Aged Ankle / physiopathology* Arteries / physiopathology Atherosclerosis / blood, diagnosis*, physiopathology* Biological Markers / blood Blood Pressure* Body Weights and Measures Cholesterol / blood Female Hemoglobin A, Glycosylated / analysis Homocysteine / blood Humans Male Mass Screening* / methods Middle Aged Pulse* Sex Factors Tunica Intima / physiopathology |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Hemoglobin A, Glycosylated; 0/hemoglobin A1c protein, human; 454-28-4/Homocysteine; 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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