| Autosomal dominant cramping disease. | |
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MedLine Citation:
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PMID: 2357164 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A family was studied in which four generations (16 of 41 members) suffered from painful recurrent muscle cramping. A clear pattern of autosomal dominant inheritance was noted. The cramping first developed during adolescence or early adulthood. Electromyographic analysis indicated a neurogenic origin. The cramps seemed to be due to dysfunction of the motor neurons. The mechanisms underlying this alteration are unclear and require further investigation. |
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Authors:
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K Ricker; R T Moxley |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Archives of neurology Volume: 47 ISSN: 0003-9942 ISO Abbreviation: Arch. Neurol. Publication Date: 1990 Jul |
Date Detail:
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Created Date: 1990-07-24 Completed Date: 1990-07-24 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0372436 Medline TA: Arch Neurol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 810-2 Citation Subset: AIM; IM |
Affiliation:
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Department of Neurology, University of Würzburg, West Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Electromyography Female Humans Leg Male Middle Aged Muscle Cramp / genetics* Pedigree |
| Grant Support | |
ID/Acronym/Agency:
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AM-38193/AM/NIADDK NIH HHS; DK-32884/DK/NIDDK NIH HHS; RR-00044/RR/NCRR NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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