Document Detail


Autosomal dominant central pigment epithelial and choroidal degeneration.
MedLine Citation:
PMID:  7162784     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Eight of nine individuals of a four-generation family had autosomal dominant central pigment epithelial and choroidal degeneration, which was not entirely consistent with previously described central retinal and choroidal degenerations. The early loss of the choriocapillaris with a relative sparing of the sensory retinal and pigment epithelial function is similar to central areolar choroidal degeneration. Ophthalmoscopically, however, the disease resembled the dominant progressive foveal degenerations; except that our patients additionally had multiple peripheral yellow-white lesions. An exceptional finding in our patients was the preservation of good visual acuity despite marked atrophy of the choriocapillaris.
Authors:
A S Leveille; P H Morse; J P Kiernan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Ophthalmology     Volume:  89     ISSN:  0161-6420     ISO Abbreviation:  Ophthalmology     Publication Date:  1982 Dec 
Date Detail:
Created Date:  1983-04-21     Completed Date:  1983-04-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7802443     Medline TA:  Ophthalmology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1407-13     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Child
Choroid / pathology*
Female
Fluorescein Angiography
Genes, Dominant
Humans
Male
Middle Aged
Pedigree
Pigment Epithelium of Eye / pathology*
Uveal Diseases / diagnosis,  genetics*,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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