| Autopsy report of four cases who died from Streptococcus suis infection, with a review of the literature. | |
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MedLine Citation:
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PMID: 18958507 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There was an outbreak of human Streptococcus suis (S. suis) infection in southwest China in 2005. The total number of documented patients was 204 and 38 of them died. Four cases were autopsied and are reported in this paper. The autopsies showed that multiple organs were involved, with a prominent injury of the lung, kidney, and intestine. The essential pathologic changes were multiple microthrombi (hyaline thrombi) formation in the capillaries of various organs and tissues, accompanied by congestion and hemorrhage. The pathogen of the disease was S. suis, serotype 2, which was confirmed by means of germ culture of the heart, blood, and tissue samples at the Chinese Center for Disease Control and Prevention (China CDC). The autopsy diagnosis of all four cases was septicemia with disseminated intravascular coagulation (DIC). The cause of death was toxic shock with multi-organ dysfunction. Combined with the epidemic features, clinical manifestations, etiological, and autopsy findings, it accorded with streptococcal toxic shock syndrome (STSS). |
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Authors:
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Q-P Yang; W-P Liu; L-X Guo; Y Jiang; G-D Li; Y-Q Bai; S-H Li; T Wu; H-Q Jing |
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Publication Detail:
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Type: Case Reports; Journal Article; Review Date: 2008-10-29 |
Journal Detail:
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Title: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology Volume: 28 ISSN: 1435-4373 ISO Abbreviation: Eur. J. Clin. Microbiol. Infect. Dis. Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-05-28 Completed Date: 2009-06-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8804297 Medline TA: Eur J Clin Microbiol Infect Dis Country: Germany |
Other Details:
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Languages: eng Pagination: 447-53 Citation Subset: IM |
Affiliation:
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Department of Pathology, West China Hospital of Sichuan University, Chengdu, China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Autopsy China / epidemiology Disease Outbreaks* Fatal Outcome Humans Intestines / pathology Kidney / pathology Lung / pathology Male Middle Aged Sepsis / epidemiology*, microbiology, pathology* Serotyping Shock, Septic / epidemiology, microbiology, pathology Streptococcal Infections / epidemiology*, microbiology, pathology* Streptococcus suis / classification, isolation & purification* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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