Document Detail

Autopsy finding of the Sapien XT valve from a patient who died suddenly after transcatheter aortic valve replacement.
MedLine Citation:
PMID:  23277347     Owner:  NLM     Status:  Publisher    
An 89-year-old woman with severe aortic stenosis underwent transfemoral aortic valve replacement. The postoperative course was uneventful except transient bradycardia immediately after the procedure. Echocardiographic finding showed excellent valvular function. After discharge, the patient died suddenly. Autopsy findings showed compression of the atrioventricular conduction system region at the septum by the stent strut. Microscopic examination showed atrophy of the conduction fibers with eosinophilic degeneration of the cytoplasm or coagulation necrosis with pyknosis in the bundle of His and the left bundle branch. Compression by the stent strut triggering dysfunction of the conduction system could have caused fatal arrhythmic event.
Mike Saji; Tatsuya Murai; Tetsuya Tobaru; Minoru Tabata; Shuichiro Takanashi; Morimasa Takayama
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-1
Journal Detail:
Title:  Cardiovascular intervention and therapeutics     Volume:  -     ISSN:  1868-4297     ISO Abbreviation:  Cardiovasc Interv Ther     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101522043     Medline TA:  Cardiovasc Interv Ther     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Cardiology, Sakakibara Heart Institute, 3-16-1 Asahi-cho Fuchu, Tokyo, 183-0003, Japan,
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