Document Detail


Autopsy findings in botulinum toxin poisoning.
MedLine Citation:
PMID:  20533981     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
In the United States, foodborne botulism is most commonly associated with home-canned food products. Between 1950 and 2005, 405 separate outbreaks of botulism were reported to the Centers for Disease Control and Prevention (CDC). Approximately 8% of these outbreaks were attributed to commercially produced canned food products. Overall, 5-10% of persons ingesting botulinum toxin die. Few reports exist pertaining to autopsy findings in cases of foodborne botulism. Here, we report the autopsy findings of a man who died after a prolonged illness caused by botulinum toxin exposure likely attributable to a commercially prepared food source. Despite extensive testing, our histopathologic findings were nonspecific. We therefore conclude that the forensic pathologist must become familiar with the neurotoxicity syndrome associated with this illness. Maintaining vigilance for botulism by carefully reviewing the decedent's clinical history will aid in the early identification and control of outbreaks, either foodborne or terrorism-related.
Authors:
Kelly G Devers; Jeffrey S Nine
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of forensic sciences     Volume:  55     ISSN:  1556-4029     ISO Abbreviation:  J. Forensic Sci.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375370     Medline TA:  J Forensic Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1649-51     Citation Subset:  IM    
Copyright Information:
2010 American Academy of Forensic Sciences. Published 2010. This article is a U.S. Government work and is in the public domain in the U.S.A.
Affiliation:
University of New Mexico Health Sciences Center, Department of Pathology, MSC08 4640, 1 University of New Mexico, Albuquerque, NM 87131, USA. kdevers@salud.unm.edu
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