Document Detail


An autopsy case of secondary iron-overload cardiomyopathy.
MedLine Citation:
PMID:  23774549     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A woman over 70 years of age presented with anemia and appetite loss. She had no history of blood transfusions, although she had been receiving iron infusions for anemia for seven years. She had an elevated serum ferritin level (7,951 ng/mL) one month before admission. Abdominal computed tomography showed increased hepatic density and echocardiography showed normal heart valves and heart-wall motion. The patient eventually experienced atrial tachycardia and atrial fibrillation and died of heart failure. An autopsy revealed iron deposits in the liver, pancreas, adrenal glands, thyroid gland, gastric mucosa and myocardium. Iron-overload cardiomyopathy was diagnosed based on the iron deposits, myocardial disarray and interstitial fibrosis.
Authors:
Toshiyuki Kobayashi; Hiroshi Tadokoro; Koshi Matsumoto
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  52     ISSN:  1349-7235     ISO Abbreviation:  Intern. Med.     Publication Date:  2013  
Date Detail:
Created Date:  2013-06-18     Completed Date:  2014-02-10     Revised Date:  2014-03-31    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1369-73     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aged
Autopsy
Cardiomyopathies / diagnosis*,  etiology*,  metabolism
Female
Hemosiderosis / complications,  diagnosis,  metabolism
Humans
Iron / metabolism
Iron Overload / complications*,  diagnosis*,  metabolism
Liver / metabolism,  pathology
Myocardium / metabolism,  pathology
Tissue Distribution
Chemical
Reg. No./Substance:
E1UOL152H7/Iron
Comments/Corrections
Comment In:
Intern Med. 2014;53(4):351   [PMID:  24531101 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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