Document Detail

Autonomic studies in hypertensive patient with unusual sexual dysfunction: response to reserpine.
MedLine Citation:
PMID:  11198488     Owner:  NLM     Status:  MEDLINE    
The authors examined a 48-year-old man with a history of hypertension (6 years) and a history of erection and ejaculation during cold exposure and confrontation with fear (20 years). Exposing the foot to cold water induced ejaculation in 10 seconds. A variety of antihypertensive medications resulted in control of hypertension, without improvement in ejaculatory dysfunction. Similarly, prazosin controlled the blood pressure, but not the episodes of ejaculation. Treatment with reserpine resulted in gradual reduction in blood pressure and an improvement in ejaculatory dysfunction.
K K Deepak; B Bhargava; R Narang; B H Paudel; P K Rai; S Saxena
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical autonomic research : official journal of the Clinical Autonomic Research Society     Volume:  10     ISSN:  0959-9851     ISO Abbreviation:  Clin. Auton. Res.     Publication Date:  2000 Oct 
Date Detail:
Created Date:  2001-01-23     Completed Date:  2001-04-19     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9106549     Medline TA:  Clin Auton Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  313-5     Citation Subset:  IM    
Department of Physiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi.
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MeSH Terms
Autonomic Nervous System / physiopathology*
Blood Pressure / drug effects
Cold Temperature / adverse effects
Dose-Response Relationship, Drug
Drug Therapy, Combination
Ejaculation / drug effects
Heart Rate / drug effects
Hypertension / complications,  drug therapy*
Middle Aged
Penile Erection / drug effects
Prazosin / therapeutic use
Reaction Time / drug effects
Reserpine / therapeutic use*
Sexual Dysfunction, Physiological / complications,  diagnosis,  drug therapy*,  physiopathology*
Treatment Outcome
Valsalva Maneuver
Reg. No./Substance:
19216-56-9/Prazosin; 50-55-5/Reserpine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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