Document Detail

Autonomic and somatic responses evoked by stimulation of the cerebellar uvula in the conscious rabbit.
MedLine Citation:
PMID:  2340159     Owner:  NLM     Status:  MEDLINE    
The present study has investigated the effects of electrical stimulation of the cerebellar posterior cortex in the conscious rabbit. Stimulation of lobule IX (the uvula) elicited an increase in mean arterial blood pressure and heart rate, accompanied by EEG desynchronization, pupillary dilatation and a specific motor reaction, consisting of pricking of the ears, neck stiffening and running movements. Stimulation of lobule VIII was ineffective in evoking equivalent responses. The administration of barbiturates reversed the cardiovascular response to uvula stimulation, producing a fall in mean arterial pressure. The characteristics of the pattern of responses obtained, together with the anatomical and electrophysical observations provided in the preceding paper (Bradley, Ghelarducci, La Noce, Paton, Spyer & Withington-Wray, 1990), suggest a possible involvement of uvula cortex in the expression of the alerting reaction in the rabbit.
D J Bradley; B Ghelarducci; A La Noce; K M Spyer
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Experimental physiology     Volume:  75     ISSN:  0958-0670     ISO Abbreviation:  Exp. Physiol.     Publication Date:  1990 Mar 
Date Detail:
Created Date:  1990-06-25     Completed Date:  1990-06-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9002940     Medline TA:  Exp Physiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  179-86     Citation Subset:  IM    
Department of Physiology and Biochemistry, University of Pisa, Italy.
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MeSH Terms
Analysis of Variance
Autonomic Nervous System / drug effects,  physiology*
Barbiturates / pharmacology
Blood Pressure / drug effects,  physiology
Cerebellar Cortex / drug effects,  physiology*
Electric Stimulation
Heart Rate / drug effects,  physiology
Motor Neurons / drug effects,  physiology*
Pupil / drug effects,  physiology
Reg. No./Substance:

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