Document Detail

Autonomic functions in Buerger's disease.
MedLine Citation:
PMID:  11883155     Owner:  NLM     Status:  MEDLINE    
One of the pathophysiological features in Buerger's disease, i.e. thromboangitis obliterans (TAO), is vasospastic phenomena. So autonomic reactivity was evaluated in 12 patients of Buerger's disease (1-6 years duration) and compared to age and sex matched controls (nonsmokers). Basal heart rate was significantly (P < 0.001) higher without any variation in blood pressure in TAO group compared to controls. Valsalva ratio (P < 0.01) and 30:15 ratio (P < 0.001) were increased without any effect on E:I ratio in TAO group versus controls. On head up tilt (HUT), there was significant (P < 0.001) fall in blood pressure in TAO group compared to controls. On cold pressure test (CPT), systolic blood pressure was reduced significantly (P < 0.01) in TAO group than that of controls, however, diastolic blood pressure showed no change in two groups. Responses indicate towards lower sympathetic reactivity in Buerger's patients.
K Singh; S Sood
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of physiology and pharmacology     Volume:  45     ISSN:  0019-5499     ISO Abbreviation:  Indian J. Physiol. Pharmacol.     Publication Date:  2001 Oct 
Date Detail:
Created Date:  2002-03-08     Completed Date:  2002-08-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0374707     Medline TA:  Indian J Physiol Pharmacol     Country:  India    
Other Details:
Languages:  eng     Pagination:  470-4     Citation Subset:  IM    
Department of Physiology, Pt. B. D. Sharma, Postgraduate, Institute of Medical Sciences (PGIMS), Rohtak-124 001.
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MeSH Terms
Autonomic Nervous System / physiopathology*
Blood Pressure
Heart Rate
Thromboangiitis Obliterans / physiopathology*

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