Document Detail

Autonomic dysfunction in the Guillain-Barré syndrome. Hemodynamic and neurobiochemical studies.
MedLine Citation:
PMID:  7356703     Owner:  NLM     Status:  MEDLINE    
In 12 patients suffering from the Guillain-Barré syndrome, with autonomic dysfunction, a hemodynamic study was performed and biological counts of neurotransmitter metabolites were repeatedly taken in the urine, the plasma and the lumber cerebrospinal fluid. In the course of the Guillain-Barré syndrome with autonomic dysfunction the changes in hemodynamic indices suggest a state of sympathetic hyperactivity. There is an increase in cerebrospinal neurotransmitter metabolite levels with an increase in central cathecholaminergic and serotoninergic activity. The findings point to an interference of central structures in the sympathetic hyperactivity observed.
A Durocher; B Servais; M Caridroix; C Chopin; F Wattel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Intensive care medicine     Volume:  6     ISSN:  0342-4642     ISO Abbreviation:  Intensive Care Med     Publication Date:  1980  
Date Detail:
Created Date:  1980-03-24     Completed Date:  1980-03-24     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7704851     Medline TA:  Intensive Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  3-6     Citation Subset:  IM    
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MeSH Terms
Catecholamines / urine
Dysautonomia, Familial / physiopathology*
Hydroxyindoleacetic Acid / cerebrospinal fluid,  urine
Methoxyhydroxyphenylglycol / cerebrospinal fluid
Middle Aged
Polyradiculoneuropathy / physiopathology*
Serotonin / blood
Vanilmandelic Acid / urine
Reg. No./Substance:
0/Catecholamines; 50-67-9/Serotonin; 534-82-7/Methoxyhydroxyphenylglycol; 54-16-0/Hydroxyindoleacetic Acid; 55-10-7/Vanilmandelic Acid

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