Document Detail


Automation and robotics in ADME screening.
MedLine Citation:
PMID:  24981617     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The use of automated sample processing, analytics and screening technology for profiling absorption, distribution, metabolism and excretion (ADME) and physicochemical properties, early in the drug discovery process, is becoming more widespread. The use and application of these technologies is both diverse and innovative. High-throughput screening (HTS) technologies have been utilised enabling the profiling of an increased number of compounds emerging from the drug discovery process. Although the drivers for using these technologies are common, different approaches can be taken.:
Authors:
Kenneth C Saunders
Related Documents :
135667 - Combination chemotherapy with adriamycin and streptozotocin. ii. clincopharmacologic co...
9452267 - The effects of different antineoplastic agents and of pretreatment by modulators on thr...
23496217 - Lead generation: reality check on commonly held views.
23148877 - The revised ema guideline for the investigation of bioequivalence for immediate release...
22185267 - Are multimetabolite methods fit-for-purpose for supporting toxicology studies?
23737437 - Recent developments in drug therapy for cushing's disease.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Drug discovery today. Technologies     Volume:  1     ISSN:  1740-6749     ISO Abbreviation:  Drug Discov Today Technol     Publication Date:  2004 Dec 
Date Detail:
Created Date:  2014-07-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101235076     Medline TA:  Drug Discov Today Technol     Country:  England    
Other Details:
Languages:  eng     Pagination:  373-80     Citation Subset:  -    
Copyright Information:
© 2004 Elsevier Ltd . All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Metabolic screening in vitro: metabolic stability, CYP inhibition and induction.
Next Document:  In silico prediction of drug safety: despite progress there is abundant room for improvement.