| Automatic implantable cardioverter-defibrillators in Chagas' heart disease patients with malignant ventricular arrhythmias. | |
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MedLine Citation:
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PMID: 16689840 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A total of 46 consecutive Chagas' disease patients had an automatic cardioverter defibrillator implanted at our institution from October 1998 to January 2004. A retrospective longitudinal study was carried out to identity type of life-threatening ventricular arrhythmias as well as type of therapy delivered. Of these, 41 (91%) had been recovered from cardiac arrest. Five (15%) of 33 patients in whom echocardiography was done had no left ventricular function. Antiarrhythmic therapy was delivered to 37 (80%) patients during postimplant follow-up. Thirty-one of 37 (84%) patients received both shock and antitachycardia pacing, five (13%) only antitachycardia pacing, and one (3%) patient only shock. Median time to first shock was 16 days, varying from 1 to 576 days. Ventricular fibrillation was the cause of first shock in 12 patients (32%), ventricular tachycardia in 11 (29%), and ventricular tachycardia not responding to antitachycardia pacing degenerating into ventricular fibrillation in nine (24%). Five patients with ventricular tachycardia were treated with antitachycardia pacing. Probability of freedom from device discharged was 47% at 90 days, 34% at 180 days, and 9% at 360 days in the postimplant follow-up. Thus, patients with chronic Chagas' heart disease recovered from cardiac arrest have a peculiar arrhythmogenic profile characterized by a high frequency of ventricular fibrillation and no left ventricular systolic dysfunction and a short period of time for first shock. |
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Authors:
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Augusto Cardinalli-Neto; Osvaldo T Greco; Reinaldo B Bestetti |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Pacing and clinical electrophysiology : PACE Volume: 29 ISSN: 0147-8389 ISO Abbreviation: Pacing Clin Electrophysiol Publication Date: 2006 May |
Date Detail:
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Created Date: 2006-05-12 Completed Date: 2006-10-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7803944 Medline TA: Pacing Clin Electrophysiol Country: United States |
Other Details:
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Languages: eng Pagination: 467-70 Citation Subset: IM |
Affiliation:
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Department of Cardiology and Cardiovascular Surgery, Hospital de Base, Sâo José do Rio Preto Medical School, São José do Rio Preto city, Brazil. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Brazil
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epidemiology Chagas Cardiomyopathy / epidemiology*, therapy* Comorbidity Defibrillators, Implantable / statistics & numerical data* Disease-Free Survival Female Humans Incidence Longitudinal Studies Male Middle Aged Retrospective Studies Risk Assessment / methods* Risk Factors Treatment Outcome Ventricular Fibrillation / epidemiology*, prevention & control* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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