Document Detail


Automatic burst detection for the EEG of the preterm infant.
MedLine Citation:
PMID:  21896968     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
To aid with prognosis and stratification of clinical treatment for preterm infants, a method for automated detection of bursts, interburst-intervals (IBIs) and continuous patterns in the electroencephalogram (EEG) is developed. Results are evaluated for preterm infants with normal neurological follow-up at 2 years. The detection algorithm (MATLAB®) for burst, IBI and continuous pattern is based on selection by amplitude, time span, number of channels and numbers of active electrodes. Annotations of two neurophysiologists were used to determine threshold values. The training set consisted of EEG recordings of four preterm infants with postmenstrual age (PMA, gestational age + postnatal age) of 29-34 weeks. Optimal threshold values were based on overall highest sensitivity. For evaluation, both observers verified detections in an independent dataset of four EEG recordings with comparable PMA. Algorithm performance was assessed by calculation of sensitivity and positive predictive value. The results of algorithm evaluation are as follows: sensitivity values of 90% ± 6%, 80% ± 9% and 97% ± 5% for burst, IBI and continuous patterns, respectively. Corresponding positive predictive values were 88% ± 8%, 96% ± 3% and 85% ± 15%, respectively. In conclusion, the algorithm showed high sensitivity and positive predictive values for bursts, IBIs and continuous patterns in preterm EEG. Computer-assisted analysis of EEG may allow objective and reproducible analysis for clinical treatment.
Authors:
Ward Jennekens; Loes S Ruijs; Charlotte M L Lommen; Hendrik J Niemarkt; Jaco W Pasman; Vivianne H J M van Kranen-Mastenbroek; Pieter F F Wijn; Carola van Pul; Peter Andriessen
Related Documents :
22102598 - End-tidal carbon dioxide monitoring in very low birth weight infants: correlation and a...
21840538 - Bloodstream infections in very low birth weight infants with intestinal failure.
21931598 - Prediction of mortality in very premature infants: a systematic review of prediction mo...
18049148 - Implementation and evaluation of a best practice initiative. venipuncture in the well b...
10604818 - The pharmacokinetics of theophylline in premature neonates during the first few days af...
10486088 - Screening for hypercholesterolaemia in 10,000 neonates in a multi-ethnic population.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-9-06
Journal Detail:
Title:  Physiological measurement     Volume:  32     ISSN:  1361-6579     ISO Abbreviation:  -     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-9-7     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9306921     Medline TA:  Physiol Meas     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1623-1637     Citation Subset:  -    
Affiliation:
Department of Clinical Physics, Máxima Medical Centre, Veldhoven, The Netherlands. Department of Applied Physics, Eindhoven University of Technology, Eindhoven, The Netherlands.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Simulation study on potential accuracy gains from dual energy CT tissue segmentation for low-energy ...
Next Document:  Advanced Poincaré plot analysis differentiates between hypertensive pregnancy disorders.