| Automated remote transapical wound closure system study. | |
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MedLine Citation:
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PMID: 21958800 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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PURPOSE: A readily applied and reliable means to create and close transapical wound access sites through a small intercostal opening could benefit many cardiac patients. Using relevant surgical tissue models, this research evaluated a new approach to enable single-port transapical wound site closure toward the eventual development of safe percutaneous access to the left ventricle. DESCRIPTION: Novel techniques and technologies were developed and successfully tested for remote automated placement of 2 pledgeted horizontal mattress sutures delivered concentrically around a transmural apical guidewire, which provided a tract to enable therapeutic intervention. Mechanical pledgeted knots secured these sutures after cannula removal. EVALUATION: Automated transapical closures were created in 47 ex vivo porcine hearts and in 10 human cadavers, 8 through a thoracotomy and 2 thoracoscopically. Automated apical closures achieved hemostasis in an acute beating heart thoracotomy model in 3 anesthetized pigs. An ex vivo porcine heart pressurized infusate model demonstrated the intraventricular pressure tolerated by automated closures (mean, 327 mm Hg) compared with hand-sutured closures (mean, 303 mm Hg). CONCLUSIONS: All automated apical closures were effective. Early results encourage further evaluation. |
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Authors:
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Peter A Knight; Jude S Sauer; James W Kaufer; Candice L Wilshire |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Annals of thoracic surgery Volume: 92 ISSN: 1552-6259 ISO Abbreviation: Ann. Thorac. Surg. Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-09-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 15030100R Medline TA: Ann Thorac Surg Country: Netherlands |
Other Details:
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Languages: eng Pagination: 1494-8 Citation Subset: AIM; IM |
Copyright Information:
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Copyright © 2011 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Surgery, Division of Cardiothoracic Surgery, University of Rochester School of Medicine and Dentistry, Rochester, New York. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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