| Automated digital cell morphology identification system (CellaVision DM96) is very useful for leukocyte differentials in specimens with qualitative or quantitative abnormalities. | |
| | |
MedLine Citation:
|
PMID: 23286314 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
INTRODUCTION: The CellaVision DM96 system (CellaVision AB, Lund, Sweden) was developed as one of the automated digital cell morphology analyzer for determining leukocyte differential counts in peripheral blood smears (PBS) and we evaluated this system. METHODS: A total of 308 PB samples with abnormalities were analyzed in this study. For each sample, manual differential counts were performed by two independent technologists, and the CellaVision DM96 system was applied in duplicate. Correlations between the two methods and ability of this system to identify six abnormalities were assessed. RESULTS: The correlation coefficients between two methods were consistently high, ranged from 0.864 to 0.992. The sensitivity, specificity, positive predictive value, negative predictive values of this system for the identification of abnormalities were consistently high, especially for blasts (98.2%, 99.2%, 96.6%, 99.6%). When the instrument was ordered to count 300 or 500 cells from the operator, better performance was demonstrated than 100 cells in the leukopenic samples by sacrificing only 40 s/slide in average. CONCLUSIONS: The CellaVision DM96 system is useful in the clinical laboratory providing comparative accuracy compared with manual counts in samples with abnormalities. In leukopenic samples, report quality can be improved by ordering to count 300 or 500 cells from the operator without severe prolongation of turnaround time. |
| | |
Authors:
|
S H Park; C-J Park; M-O Choi; M-J Kim; Y-U Cho; S Jang; H-S Chi |
Related Documents
:
|
21563254 - Imaging of blood flow using hyperpolarized [(13)c]urea in preclinical cancer models. 23304654 - Gene transfection efficacy assessment of human cervical cancer cells using dual-mode fl... 12503644 - Hemimegalencephaly in tuberous sclerosis complex. 21297894 - Openpet: a flexible electronics system for radiotracer imaging. 23303694 - Mixed-domain edge-aware image manipulation. 19144014 - Production of cloned miniature pigs by enucleation using the spindle view system. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2013-1-3 |
Journal Detail:
|
Title: International journal of laboratory hematology Volume: - ISSN: 1751-553X ISO Abbreviation: Int J Lab Hematol Publication Date: 2013 Jan |
Date Detail:
|
Created Date: 2013-1-4 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101300213 Medline TA: Int J Lab Hematol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
© 2013 Blackwell Publishing Ltd. |
Affiliation:
|
Department of Laboratory Medicine, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Molecular divergence in tropical tree populations occupying environmental mosaics.
Next Document: Self-Assembly of Arg-Phe Nanostructures via the Solid-Vapor Phase Method.