| Automated classification of peripheral distal by-pass geometries reconstructed from medical data. | |
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MedLine Citation:
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PMID: 15519339 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Abnormal haemodynamic conditions are implicated in the development of anastomotic myointimal hyperplasia (MIH). However, these conditions are difficult to determine in vivo, prompting research using ex vivo idealised models. To relate the understanding gained in idealised geometries to anatomically correct conditions we have investigated a reproducible approach to classify in vivo distal graft anastomoses and their inter-patient variability. In vivo distal anastomotic geometries were acquired by magnetic resonance (MR) angiography from 13 patients who had undergone infrageniculate autologous venous by-pass surgery. On average, the images were acquired 2 weeks post-operatively. Five patients also underwent repeat examinations 2 to 7 weeks later. For each geometry, the surface of the arterial lumen is represented by the zero level set of an implicit function constructed from radial basis functions that minimise curvature. The three-dimensional binary image created from the interpolated surface is processed using a skeletonisation algorithm to obtain the centreline of each branch in the geometry. This allows for the measurement of the branching angles between straight line approximations of the centrelines of each vessel, averaging them over a characteristic length of each anastomosis. The main finding in the application of the proposed classification methodology to this set of patients is that the spectrum of anastomoses can be reduced to a small subset of cases characterised by two angles: the angle between the graft and the plane of the host artery and the angle between the graft and the proximal branch of the artery. |
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Authors:
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S Giordana; S J Sherwin; J Peiró; D J Doorly; Y Papaharilaou; C G Caro; N Watkins; N Cheshire; M Jackson; C Bicknall; V Zervas |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of biomechanics Volume: 38 ISSN: 0021-9290 ISO Abbreviation: J Biomech Publication Date: 2005 Jan |
Date Detail:
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Created Date: 2004-11-02 Completed Date: 2005-02-15 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0157375 Medline TA: J Biomech Country: United States |
Other Details:
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Languages: eng Pagination: 47-62 Citation Subset: IM |
Affiliation:
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Department of Aeronautics, Biofluids Group, Imperial College London, London SW7 2AZ, UK. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Algorithms Anastomosis, Surgical Anatomy, Cross-Sectional Arteries / pathology Cerebral Revascularization* Geniculate Bodies / blood supply*, pathology, surgery* Humans Image Processing, Computer-Assisted Imaging, Three-Dimensional Magnetic Resonance Angiography Models, Cardiovascular* Postoperative Period Reproducibility of Results Transplantation, Autologous Veins / transplantation |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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