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Automated Solid-Phase Synthesis of β-Mannuronic Acid Alginates.
MedLine Citation:
PMID:  22389322     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The automated solid-phase assembly of oligomannuronic acid alginates, key exopolysaccharides of the opportunistic Gram-negative bacterium Pseudomonas aeruginosa, has been achieved through the use of mannuronic acid building blocks in a fully automated carbohydrate synthesizer. G. A. van der Marel, J. D. C. Codée, and co-workers report in their Communication (DOI: 10.1002/anie.201108744) how mannuronic acid alginate fragments with up to 12 cis-mannosidic linkages have been assembled by this method.
Authors:
Marthe T C Walvoort; Hans van den Elst; Obadiah J Plante; Lenz Kröck; Peter H Seeberger; Herman S Overkleeft; Gijsbert A van der Marel; Jeroen D C Codée
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-3-2
Journal Detail:
Title:  Angewandte Chemie (International ed. in English)     Volume:  -     ISSN:  1521-3773     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-3-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370543     Medline TA:  Angew Chem Int Ed Engl     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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