| Automated Solid-Phase Synthesis of β-Mannuronic Acid Alginates. | |
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MedLine Citation:
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PMID: 22334421 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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A big step towards routine: The title synthesis provides of mannuronic acid alginate fragments featuring up to 12 cis-mannosidic linkages, in multi-milligram quantities (see scheme; Bn=benzyl, Lev=levulinoyl). Mannuronic acid building blocks were used in a second-generation carbohydrate synthesizer to secure the stereoselective introduction of the β-mannosidic bonds in a fully automated fashion. |
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Authors:
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Marthe T C Walvoort; Hans van den Elst; Obadiah J Plante; Lenz Kröck; Peter H Seeberger; Herman S Overkleeft; Gijsbert A van der Marel; Jeroen D C Codée |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-2-14 |
Journal Detail:
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Title: Angewandte Chemie (International ed. in English) Volume: - ISSN: 1521-3773 ISO Abbreviation: - Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-2-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370543 Medline TA: Angew Chem Int Ed Engl Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
Affiliation:
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Leiden Institute of Chemistry, Leiden University, P.O.Box 9502, 2300 RA Leiden (The Netherlands). |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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