Document Detail


Automated RFLP pattern comparison and similarity coefficient calculation for rapid delineation of new and distinct phytoplasma 16Sr subgroup lineages.
MedLine Citation:
PMID:  18842858     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Phytoplasmas are cell wall-less bacteria that cause numerous diseases in several hundred plant species. During adaptation to transkingdom parasitism in diverse plant and insect hosts, phytoplasma evolution has given rise to widely divergent lineages. Since phytoplasmas cannot be cultured in a cell-free medium, measurable phenotypic characters suitable for conventional microbial classification are mostly inaccessible. Currently, phytoplasma differentiation and classification are mainly dependent on restriction fragment length polymorphism (RFLP) analysis of 16S rRNA gene sequences. Extending our recent efforts in the exploitation of computer-simulated 16S rRNA gene RFLP analysis and virtual gel plotting for rapid classification of phytoplasmas, we have developed a Perl program for automated RFLP pattern comparison and similarity coefficient calculation. This program streamlines virtual RFLP pattern analysis and has led to the establishment of a criterion for phytoplasma 16Sr subgroup classification and to the delineation of new and distinct subgroup lineages in the clover proliferation phytoplasma group (16SrVI).
Authors:
Wei Wei; Ing-Ming Lee; Robert E Davis; Xiaobing Suo; Yan Zhao
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  International journal of systematic and evolutionary microbiology     Volume:  58     ISSN:  1466-5026     ISO Abbreviation:  Int. J. Syst. Evol. Microbiol.     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-10-09     Completed Date:  2008-11-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100899600     Medline TA:  Int J Syst Evol Microbiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  2368-77     Citation Subset:  IM    
Affiliation:
Molecular Plant Pathology Laboratory, USDA-Agricultural Research Service, Beltsville, MD 20705, USA.
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MeSH Terms
Descriptor/Qualifier:
Bacterial Typing Techniques
Computer Simulation
DNA Restriction Enzymes / chemistry
DNA, Bacterial / genetics
Genes, Bacterial
Genes, rRNA
Medicago / microbiology
Pattern Recognition, Automated
Phylogeny
Phytoplasma / classification*,  enzymology,  genetics*
Plant Diseases / microbiology
Polymorphism, Restriction Fragment Length*
RNA, Ribosomal, 16S / genetics*
Sequence Analysis, DNA
Software*
Chemical
Reg. No./Substance:
0/DNA, Bacterial; 0/RNA, Ribosomal, 16S; EC 3.1.21.-/DNA Restriction Enzymes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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