| Autologous serum eyedrops: literature review and implications for transfusion medicine specialists. | |
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MedLine Citation:
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PMID: 18410252 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Persistent corneal epithelial defects (CEDs) are caused by many diseases that are usually associated with decreased production of tears or reduced corneal sensitivity. Although surgical treatments are available for severe cases, CEDs are still difficult for ophthalmologists to treat. One treatment for CEDs that is uncommonly used in the United States is autologous serum eyedrops (ASEs). The first application of ASEs was described in 1984. This landmark report was followed by multiple studies that carefully evaluated the epithelial-promoting properties of ASEs and refined the means of ASE preparation. A number of clinical studies suggested the efficacy of ASEs in various ophthalmologic conditions. This article reviews the efficacy and complications of ASE use reported in these studies. Given that ophthalmologists may consult the blood bank to request ASEs, transfusion medicine physicians should be aware of the issues related to ASE preparation, storage, and potential utility. |
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Authors:
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Chisa Yamada; Karen E King; Paul M Ness |
Publication Detail:
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Type: Journal Article; Review Date: 2008-04-10 |
Journal Detail:
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Title: Transfusion Volume: 48 ISSN: 0041-1132 ISO Abbreviation: Transfusion Publication Date: 2008 Jun |
Date Detail:
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Created Date: 2008-08-20 Completed Date: 2008-09-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0417360 Medline TA: Transfusion Country: United States |
Other Details:
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Languages: eng Pagination: 1245-55 Citation Subset: IM |
Affiliation:
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Transfusion Medicine Division, Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA. cyamada2@jhmi.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Autoantigens
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therapeutic use* Blood Transfusion* Cornea / cytology, physiology Epithelium / physiology Humans Infertility Ophthalmic Solutions / pharmacology*, therapeutic use Serum |
| Chemical | |
Reg. No./Substance:
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0/Autoantigens; 0/Ophthalmic Solutions |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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