Document Detail

Autologous glutaraldehyde-treated pericardial valved conduit: an experimental study.
MedLine Citation:
PMID:  7646159     Owner:  NLM     Status:  MEDLINE    
Extracardiac conduits in the form of allografts and synthetic tubes containing heterograft valves have been used widely in the management of ventricular outflow abnormalities and for establishing ventriculoarterial continuity. These procedures are limited by long-term calcification as well as by formation of neointimal peel, necessitating reoperation. In an effort to continue the search for an alternative conduit, we designed and evaluated a valved sinus-bearing conduit fashioned out of autologous pericardium treated with glutaraldehyde. The construction of the conduit is described. The results of implantation of these conduits in 12 sheep showed no progression of gradients, fresh regurgitation, or evidence of wall or cusp calcification 9 months after implantation.
M N Kumar; G Prabakar; N Kumar; M Shahid; A E Becker; C M Duran
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  60     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  1995 Aug 
Date Detail:
Created Date:  1995-09-20     Completed Date:  1995-09-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  S200-4     Citation Subset:  AIM; IM    
Department of Cardiovascular Diseases, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
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MeSH Terms
Blood Vessel Prosthesis*
Heart Valve Prosthesis*
Transplantation, Autologous
Reg. No./Substance:

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