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Autologous fat transplantation versus adipose-derived stem cell-enriched lipografts: a study.
MedLine Citation:
PMID:  21813882     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Background: Several techniques for lipoinjection have been described in the literature. Recently, the role of adult stem cells in adipose tissue has gained interest. Objectives: The authors compare autologous fat transplantation to adipose-derived stem cell-enriched lipografts. Methods: A group of 20 patients with congenital or acquired facial tissue defects were included in this study and randomly divided into two groups. Ten patients were treated with autologous fat transplantation (Group A; 12-165 mL per session), and the remaining ten were treated with adipose-derived stem cell-enriched lipografts (Group B; 8-155 mL per session). Overall patient satisfaction after both treatments was evaluated at six, 12, and 18 months after the initial surgical procedure. Results: In Group A, three patients achieved aesthetically-acceptable results after the first treatment; the remaining seven patients required additional sessions. In Group B, all patients required only one treatment. Analysis of patient satisfaction in the first six months clearly demonstrated better results in Group B. However, by the 18-month evaluation, there was no statistical difference between the two groups in terms of patient satisfaction. Conclusions: Adipose-derived stem cell-enriched lipografts produced aesthetically-acceptable results without the need for repeat treatment sessions, which are necessary with autologous fat transplantation. Further long-term studies are necessary to confirm the favorable results seen in this study.
Authors:
Aris Sterodimas; Jose de Faria; Beatriz Nicaretta; Filippo Boriani
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Aesthetic surgery journal / the American Society for Aesthetic Plastic surgery     Volume:  31     ISSN:  1527-330X     ISO Abbreviation:  Aesthet Surg J     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-08-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9707469     Medline TA:  Aesthet Surg J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  682-93     Citation Subset:  IM    
Affiliation:
Dr. Sterodimas and Dr. de Faria are consultant plastic surgeons in the Department of Plastic Surgery, Pontifical Catholic University of Rio de Janeiro and the Carlos Chagas Post-Graduate Medical Institute, Rio de Janeiro, Brazil.
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