Document Detail

Autologous fat injection for vocal cord medialization in the canine larynx.
MedLine Citation:
PMID:  1895847     Owner:  NLM     Status:  MEDLINE    
This study examined the use of autologous fat as an alternative to Teflon and collagen as the implantable material in vocal cord medialization. Five animals underwent left recurrent laryngeal nerve sections with subsequent fat harvest and implantation into the left true vocal cords. Three animals were killed after 48 hours and 2 after 3 weeks; their larynges were examined with light microscopy. The results of the 48-hour samples show mode-rate acute inflammation and few areas of focal necrosis. The 3-week samples show no necrotic foci, minimal foreign-body reaction, and maintenance of structure and volume of the injected fat. Autologous fat may prove to be a valuable alternative to nonautologous injectable material in vocal cord augmentation.
D P Hill; A D Meyers; J Harris
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Laryngoscope     Volume:  101     ISSN:  0023-852X     ISO Abbreviation:  Laryngoscope     Publication Date:  1991 Apr 
Date Detail:
Created Date:  1991-10-22     Completed Date:  1991-10-22     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  8607378     Medline TA:  Laryngoscope     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  344-8     Citation Subset:  IM    
Department of Otolaryngology/Head and Neck Surgery, University of Colorado Health Sciences Center, Denver 80262.
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MeSH Terms
Adipose Tissue*
Foreign-Body Reaction / pathology
Hemorrhage / pathology
Inflammation / pathology
Necrosis / pathology
Vocal Cord Paralysis / pathology,  therapy*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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