| Autologous fat injection to treat leakage around tracheoesophageal puncture. | |
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MedLine Citation:
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PMID: 12430126 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To evaluate prospectively autologous fat injection as a treatment for leakage around tracheoesophageal puncture. PATIENTS AND METHODS: For ten patients who exhibited leakage of saliva or liquid around their tracheoesophageal puncture, autologous fat injection was carried out into the tracheoesophageal wall around the maintained prosthesis. Short-term success was evaluated at one month, and long-term follow-up was continued as long as the patients remained alive. The effectiveness of the procedure was evaluated based on the presence or absence of leakage around the puncture as the patient swallowed methylene blue liquid. Patients were adjudged completely improved when no leakage of blue liquid was observed, partially improved when a slight stasis was evident, or unimproved when a marked leakage of blue liquid was noted. RESULTS: Short-term success was achieved for 6 patients, 2 patients partially improved, and the procedure failed for 2 others. Long-term success (from 10 to 65 months) was achieved in all 4 of the completely improved patients who were free of disease, including 1 patient who required an additional injection. Removal of the puncture was later carried out in the 2 others for cervical node metastases or tracheal tumor. Definitive or transitional puncture closure or removal of the prosthesis was required in 3 partially or unimproved patients, whereas 1 partially improved patient died of lung metastasis 3 months later. CONCLUSIONS: Fat injection around a voice prosthesis is a procedure that may be conducted as an alternative to other conservative techniques to decrease the size of the puncture. Close endoscopic observation is required however to eliminate secondary tumor that might expand the size of the puncture. |
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Authors:
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Sophie Périé; Xie Ming; Eddy Dewolf; Jean Lacau St Guily |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: American journal of otolaryngology Volume: 23 ISSN: 0196-0709 ISO Abbreviation: Am J Otolaryngol Publication Date: 2002 Nov-Dec |
Date Detail:
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Created Date: 2002-11-13 Completed Date: 2003-03-27 Revised Date: 2007-07-24 |
Medline Journal Info:
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Nlm Unique ID: 8000029 Medline TA: Am J Otolaryngol Country: United States |
Other Details:
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Languages: eng Pagination: 345-50 Citation Subset: IM |
Copyright Information:
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Copyright 2002, Elsevier Science (USA). All rights reserved.) |
Affiliation:
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Service d'Oto-Rhino-Laryngologie et de Chirurgie Cervico-Faciale, Faculté de Médecine Saint Antoine, Université Paris VI, Hôpital Tenon, 4 rue de la Chine, 75020 Paris, France. |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adipose Tissue
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transplantation* Aged Female Humans Injections Laryngectomy / rehabilitation Larynx, Artificial / adverse effects* Male Middle Aged Prospective Studies Punctures / adverse effects* Transplantation, Autologous Treatment Outcome |
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