| Autologous blood transfusion during emergency trauma operations. | |
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MedLine Citation:
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PMID: 20644133 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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HYPOTHESIS: Intraoperative cell salvage (CS) of shed blood during emergency surgical procedures provides an effective and cost-efficient resuscitation alternative to allogeneic blood transfusion, which is associated with increased morbidity and mortality in trauma patients. DESIGN: Retrospective matched cohort study. SETTING: Level I trauma center. PATIENTS: All adult trauma patients who underwent an emergency operation and received CS as part of their intraoperative resuscitation. The CS group was matched to a no-CS group for age, sex, Injury Severity Score, mechanism of injury, and operation performed. MAIN OUTCOME MEASURES: Amount and cost of allogeneic transfusion of packed red blood cells and plasma. RESULTS: The 47 patients in the CS group were similar to the 47 in the no-CS group for all matched variables. Patients in the CS group received an average of 819 mL of autologous CS blood. The CS group received fewer intraoperative (2 vs 4 U; P = .002) and total (4 vs 8 U; P < .001) units of allogeneic packed red blood cells. The CS group also received fewer total units of plasma (3 vs 5 U; P = .03). The cost of blood product transfusion (including the total cost of CS) was less in the CS group ($1616 vs $2584 per patient; P = .004). CONCLUSION: Intraoperative CS provides an effective and cost-efficient resuscitation strategy as an alternative to allogeneic blood transfusion in trauma patients undergoing emergency operative procedures. |
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Authors:
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Carlos V R Brown; Kelli H Foulkrod; Holli T Sadler; E Kalem Richards; Dennis P Biggan; Clea Czysz; Tony Manuel |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Archives of surgery (Chicago, Ill. : 1960) Volume: 145 ISSN: 1538-3644 ISO Abbreviation: Arch Surg Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-07-20 Completed Date: 2010-08-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9716528 Medline TA: Arch Surg Country: United States |
Other Details:
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Languages: eng Pagination: 690-4 Citation Subset: AIM; IM |
Affiliation:
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Trauma Services, University Medical Center Brackenridge, 601 E 15th St., Austin, TX 78701, USA. CVRBrown@seton.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Blood Component Transfusion / economics, statistics & numerical data Blood Loss, Surgical Blood Transfusion, Autologous / economics*, statistics & numerical data* Case-Control Studies Cohort Studies Cost-Benefit Analysis Emergency Treatment / economics*, methods* Female Health Care Costs* Humans Injury Severity Score Male Middle Aged Retrospective Studies Surgical Procedures, Operative / economics*, methods* Texas Transplantation, Homologous Trauma Centers Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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